Results 321 to 330 of about 2,123,606 (402)

Molecular Targeted Therapy in Cancer

Journal of the Korean Medical Association, 2003
Nam-Su Lee, Hee-Sook Park
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

3. The Elucidation of Pathophysiology of Chronic Heart Failure and New Method of Molecular-targeted Therapy

, 2008
Masunori Matsuzaki
openalex   +4 more sources

Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma [PDF]

, 2009
Daitaro Yoshikawa, Hidenori Ojima, Akiko Kokubu, Takahiro Ochiya, S. Kasai, S Hirohashi, Tatsuhiro Shibata   +6 more
openalex   +1 more source

Molecular Targeted Therapy Approaches for BRAF Wild-Type Melanoma

Current Oncology Reports, 2016
Romany A. N. Johnpulle, Douglas B. Johnson, J. Sosman   +2 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Molecular targeted therapy in the treatment of advanced stage non‐small cell lung cancer (NSCLC)

Respirology (Carlton South. Print), 2015
Nesaretnam Barr Kumarakulasinghe, N. Zanwijk, R. Soo   +2 more
semanticscholar   +1 more source

Molecular target therapy for malignant tumor 1) The molecular target therapy.

Nihon Naika Gakkai Zasshi, 2005
openaire   +4 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Development of Resistance to Targeted Therapies Transforms the Clinically Associated Molecular Profile Subtype of Breast Tumor Xenografts

, 2008
Chad J. Creighton, Suleiman Massarweh, Shixia Huang, Anna Tsimelzon, Susan G. Hilsenbeck, C. Kent Osborne, Jiang Shou, Luca Malorni, Rachel Schiff   +8 more
openalex   +1 more source