Results 171 to 180 of about 2,569,624 (298)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Comprehensive and translational pathobiology of COVID-19 based on cellular and molecular techniques. [PDF]

Pract Lab Med
Samadani AA, Vahidi S, Babaei K, Norollahi SE, Delpasand K, Gharakhyli EA.   +5 more
europepmc   +1 more source

Improving Drought Stress Tolerance in Ramie (Boehmeria nivea L.) Using Molecular Techniques. [PDF]

Front Plant Sci, 2022
Rasheed A, Jie Y, Nawaz M, Jie H, Ma Y, Shah AN, Hassan MU, Gillani SFA, Batool M, Aslam MT, Naseem AR, Qari SH.   +11 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Molecular Techniques and Ecological Data for Taxonomically Difficult Groups: A Case Study of a Morphologically Variable New Species in the Genus <i>Chrysobothris</i> (Coleoptera: Buprestidae). [PDF]

Insects
Huang B, Wu L, Ni T, Su R, Song H, Wang R.   +5 more
europepmc   +1 more source

Standardization of molecular techniques for the detection and characterization of intestinal protozoa and other pathogens in humans. [PDF]

J Venom Anim Toxins Incl Trop Dis, 2022
Ysea MAV, Umaña MC, Fuentes SP, Campos IV, Carmona MC.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

ABCC11 Earwax Trait and Genotype Are Suitable Tools for Introductory Labs to Learn Genetics and Molecular Techniques. [PDF]

Biochem Mol Biol Educ
Ohta T, Takai R, Yoshida A, Paudel D, Giri S, Kitagawa T, Arakawa T, Kuramitsu Y, Tokutomi T.   +8 more
europepmc   +1 more source

Using FlowCam and molecular techniques to assess the diversity of Cyanobacteria species in water used for food production. [PDF]

Sci Rep, 2022
Mutoti MI, Jideani AIO, Gumbo JR.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source