Results 201 to 210 of about 15,663,299 (319)
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
Nature Biotechnology, 2016 Mingxun Wang, Jeremy J. Carver, Vanessa V. Phelan, Laura M. Sanchez, Neha Garg, Yao Peng, Don D. Nguyen, J. Watrous, Clifford A. Kapono, Tal Luzzatto-Knaan, Carla Porto, Amina Bouslimani, A. Melnik, Michael J. Meehan, Wei-Ting Liu, M. Crüsemann, Paul D. Boudreau, E. Esquenazi, Mario Sandoval-Calderón, R. Kersten, L. Pace, R. Quinn, Katherine R. Duncan, Cheng-Chih Hsu, D. Floros, R. Gavilán, Karin Kleigrewe, T. Northen, R. Dutton, D. Parrot, Erin E. Carlson, B. Aigle, C. F. Michelsen, L. Jelsbak, Christian Sohlenkamp, P. Pevzner, A. Edlund, J. McLean, J. Piel, B. Murphy, L. Gerwick, C. Liaw, Yu-Liang Yang, H. Humpf, M. Maansson, R. Keyzers, A. Sims, Andrew R. Johnson, A. Sidebottom, Brian E. Sedio, Andreas K. Klitgaard, Charles B. Larson, Cristopher A Boya P, Daniel Torres-Mendoza, D. Gonzalez, D. Silva, L. M. Marques, D. Demarque, E. Pociūtė, E. O’Neill, Enora Briand, Eric J. N. Helfrich, Eve A Granatosky, E. Glukhov, Florian Ryffel, H. Houson, H. Mohimani, Jenan J. Kharbush, Yi Zeng, J. Vorholt, Kenji L. Kurita, Pep Charusanti, K. McPhail, K. Nielsen, L. Vuong, Maryam Elfeki, Matthew F. Traxler, Niclas Engene, Nobuhiro Koyama, Oliver B. Vining, R. Baric, Ricardo R. Silva, Samantha J. Mascuch, S. Tomasi, Stefan Jenkins, V. Macherla, Thomas Hoffman, V. Agarwal, P. Williams, Jingqui Dai, R. Neupane, Joshua R. Gurr, A. M. C. Rodriguez, Anne Lamsa, Chen Zhang, Kathleen Dorrestein, B. Duggan, J. Almaliti, Pierre-Marie Allard, P. Phapale, Louis-Félix Nothias, T. Alexandrov, M. Litaudon, J. Wolfender, J. Kyle, T. Metz, Tyler Peryea, Dac-Trung Nguyen, Danielle Vanleer, P. Shinn, A. Jadhav, R. Müller, K. Waters, Wenyuan Shi, Xueting Liu, Lixin Zhang, R. Knight, P. Jensen, B. Palsson, K. Pogliano, Roger G. Linington, Marcelino Gutiérrez, N. Lopes, W. Gerwick, B. Moore, P. Dorrestein, N. Bandeira +126 moresemanticscholar +1 more sourceInfrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn +11 morewiley +1 more sourceRecurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa +15 morewiley +1 more sourceA Comparison of Molecular Techniques for Improving the Methodology in the Laboratory of Pharmacogenetics. [PDF]
Int J Mol SciPeña-Martín MC, Marcos-Vadillo E, García-Berrocal B, Heredero-Jung DH, García-Salgado MJ, Lorenzo-Hernández SM, Larrue R, Lenski M, Drevin G, Sanz C, Isidoro-García M. +10 moreeuropepmc +1 more sourceCrucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel +10 morewiley +1 more source