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HLA molecular typing

Current Opinion in Nephrology and Hypertension, 1993
HLA antigens are the major barrier to successful transplantation. Three of the seven heterodimers (HLA-A, -B, and -DR) contribute most to the immunogenicity of a mismatched organ. Although classical serology has been used in the past to phenotype donors and recipients, histocompatibility laboratories are increasingly turning to DNA-based methods to ...
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Molecular transistors based on BDT-type molecular bridges

The Journal of Chemical Physics, 2008
In this work we study the effect of electron correlations in molecular transistors with molecular bridges based on 1,4-benzene-dithiol (BDT) and 2-nitro-1,4-benzene-dithiol (nitro-BDT) by using ab initio electron propagator calculations. We find that there is no gate field effect for the BDT based transistor in accordance with the experimental data ...
W D, Wheeler, Yu, Dahnovsky
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Molecular Typing of HLA-E

2012
Human leukocyte antigen-E (HLA-E) is a non-classical HLA class I gene that shows a limited degree of polymorphism compared to the classical HLA genes. The HLA-E molecule can bind peptides derived from the leader sequence of various HLA class I alleles and some viral homologues, including CMV.
Nina, Lauterbach   +2 more
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Molecular Typing of Nontuberculous Mycobacteria

2012
The nontuberculous mycobacteria (NTM) constitute a genetically diverse group of species generally found in the (man-made) environment. Although they are frequently isolated from clinical specimens and particularly from sputum, their clinical importance is often debatable. However, in immune compromised and sometimes apparently immune competent patients
van Ingen, J, van Soolingen, D
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Molecular typing of actinomyces pyogenes isolates

Zentralblatt für Bakteriologie, 1994
The molecular characterization of 28 clinical Actinomyces pyogenes strains was attempted. SDS-PAGE protein profiles did not allow to distinguish isolates. Restriction endonuclease analysis of total DNA gave the finest differentiation between strains but the profiles were difficult to read.
V, Guérin-Faublée   +6 more
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Introduction to Molecular Typing

2010
The DNA sequences responsible for variations in most blood cell antigens have been determined. Most of these sequence variations are single nucleotide polymorphisms (SNPs) that encode for amino acid substitutions on proteins present on the surface of red blood cells or platelets. However, other variations exist, such as gene deletions and polymorphisms
JoAnn M. Moulds, Steven R. Sloan
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Molecular HLA Typing

2016
Histocompatibility antigens were first described by Snell, using inbred strains of mice. Later, Dausset, Payne, Van Rood, and others discovered that in humans antibodies to white blood cell antigens can be induced after pregnancy or transfusion. These antibodies provided the tools to define the human leukocyte antigens (HLA) (References 1–3 and ...
Malek Kamoun   +3 more
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Molecular method for typing Mycobacterium ulcerans

Journal of Clinical Microbiology, 1995
A cluster of Mycobacterium ulcerans infections has recently occurred on Phillip Island, Victoria, Australia. Previous cases of infection have generally been located around Bairnsdale in southeast Gippsland. The aim of this study was to determine the epidemiological relationship between these strains and other strains originating in Australia and Africa.
K, Jackson   +3 more
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Hepatitis A Virus: Molecular Detection and Typing

2004
Hepatitis A virus (HAV) infection is the leading cause of viral hepatitis throughout the world. HAV infection is mainly propagated via the fecal-oral route, and waterborne and foodborne outbreaks of the disease have been reported.HAV, the prototype of the genus Hepatovirus, belongs to the family Picornaviridae.
Glòria, Sánchez   +3 more
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Molecular epidemiology of coxsackievirus type B1

Archives of Virology, 2015
Coxsackievirus type B1 (CVB1) has emerged globally as the predominant enterovirus serotype and is associated with epidemics of meningitis and chronic diseases. In this report, the phylogeny of CVB1 was studied based on the VP1 sequences of 11 North African isolates and 81 published sequences.
Ichrak, Abdelkhalek   +6 more
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