Results 31 to 40 of about 3,360,583 (305)

Molecular Typing of Streptococcus pyogenes.

Nippon Saikingaku Zasshi, 1999
Streptococcus pyogenesは,ヒトに咽頭炎等の風邪様症状を起こすほか,皮膚化膿症,産辱熱,敗血症,さらには非化膿性の続発症としてリウマチ熱や急性糸球体腎炎など,さまざまな病態を引き起こすことが知られている。わが国では,小児の疾患として代表的な猩紅熱は1970年頃から減少し,これに代わるかのように1990年代初め頃より劇症型レンサ球菌感染症(TSLS)が出現するなど本菌感染症の病態が変化しているかにみえるが,いわゆる溶連菌感染症の患者数は減少していない。欧米においても,TSLSを含め侵襲性の重篤な症状を呈する本菌感染症が1980年半ば頃より増加し,分離菌株のサブタイピングがそれ以外の症状との比較のうえで行われている。本稿では,血清型の周期的な流行パターンや薬剤耐性の経年変化を含め,S.
MURASE, Toshiyuki, SUZUKI, Rieko, YAMAI, Shiro   +2 more
openaire   +3 more sources

Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans [PDF]

, 2012
Mycobacterium ulcerans (M. ulcerans), the causative agent of the devastating skin disease Buruli ulcer (BU), is characterized by an extremely low level of genetic diversity.
Danso Emelia, Röltgen, K., Gerd Pluschke, Pluschke Gerd, Yeboah-Manu, D., Katharina Röltgen, Dorothy Yeboah-Manu (120059), Gerd Pluschke (7855), Emelia Danso, Katharina Röltgen (120045), Danso, E., Pluschke, G., Kobina Assan-Ampah, Emelia Danso (120054), Dorothy Yeboah-Manu, Kobina Assan-Ampah (120049), Yeboah-Manu Dorothy, Assan-Ampah Kobina, Assan-Ampah, K., Röltgen Katharina   +19 more
core   +1 more source

Molecular endotypes of type 1 and type 2 SLE

Lupus Science & Medicine, 2023
Objective To character the molecular landscape of patients with type 1 and type 2 SLE by analysing gene expression profiles from peripheral blood. Methods Full transcriptomic RNA sequencing was carried out on whole blood samples from ...
Robert Robl, Amanda Eudy, Prathyusha S Bachali, Jennifer L Rogers, Megan Clowse, David Pisetsky, Peter Lipsky   +6 more
openaire   +3 more sources

Multilocus sequence typing breathes life into a microbial metagenome [PDF]

, 2006
Shot-gun sequencing of DNA isolated from the environment and the assembly of metagenomes from the resulting data has considerably advanced the study of microbial diversity.
Vandamme Peter, Dowson, Chris G., Mahenthiralingam Eshwar, Dowson Chris G., Adam Baldwin, Pavel Drevinek, Vandamme, Peter, Elke Vanlaere, John J LiPuma, Vanlaere, Elke, Dowson, Christopher G., LiPuma, John J., Drevinek, Pavel, LiPuma John J., Baldwin Adam, Peter Vandamme, Baldwin, Adam, Chris G Dowson, Eshwar Mahenthiralingam, Drevinek Pavel, Vanlaere Elke, Dowson, Chris G, Mahenthiralingam, Eshwar, LiPuma, John J   +23 more
core   +2 more sources

Genetic Relationships among Reptilian and Mammalian Campylobacter fetus Strains Determined by Multilocus Sequence Typing [PDF]

, 2010
Reptile Campylobacter fetus isolates and closely related strains causing human disease were characterized by multilocus sequence typing. They shared similar to 90% nucleotide sequence identity with classical mammalian C.
Pruckler, J., Dep Infectieziekten Immunologie, Fitzgerald, C., van Bergen, M.A.P., Marcel A. P. van Bergen, Bergen, M.A.P., van, Robert J. Owen, Tu, Z.C., Kate E. Dingle, Janet Pruckler, Blaser, M.J., van Bergen, M.A., Strategic Infection Biology, Dingle, K.E., Zheng-Chao Tu, Collette Fitzgerald, Lawson, A.J., Wagenaar, J.A., Martin J. Blaser, Andrew J. Lawson, Jaap A. Wagenaar, Owen, R.J.   +21 more
core   +2 more sources

Mutational Analysis of TYR, OCA2, and SLC45A2 Genes in Chinese Families with Oculocutaneous Albinism

Molecular Genetics & Genomic Medicine, 2019
Background Oculocutaneous albinism (OCA) is a group of heterogeneous autosomal recessive genetic disorder of melanin synthesis results in hypopigmented hair, skin, and eyes.
Ye Lin, Xihui Chen, Ying Yang, Fengyu Che, Sijia Zhang, Lijuan Yuan, Yuanming Wu   +6 more
doaj   +1 more source

Novel SLCO2A1 mutations cause gender-differentiated pachydermoperiostosis

Endocrine Connections, 2018
Primary hypertrophic osteoarthropathy (PHO) is a rare familial disorder with reduced penetrance for females. The genetic mutations associated with PHO have been identified in HPGD and SLCO2A1, which involved in prostaglandin E2 metabolism.
Lijuan Yuan, Xihui Chen, Ziyu Liu, Dan Wu, Jianguo Lu, Guoqiang Bao, Sijia Zhang, Lifeng Wang, Yuanming Wu   +8 more
doaj   +1 more source

Multilocus sequence typing as a replacement for serotyping in Salmonella enterica [PDF]

, 2012
Salmonella enterica subspecies enterica is traditionally subdivided into serovars by serological and nutritional characteristics. We used Multilocus Sequence Typing (MLST) to assign 4,257 isolates from 554 serovars to 1092 sequence types (STs).
Uesbeck, Alexandra, Hales, James, Satheesh Nair, Wain John, Krauland, Mary G., Harbottle Heather, Mary G. Krauland (157219), Zhou, Z, Hale, JL, Brisse Sylvain, Brisse, S., Nair, S, Alexandra Uesbeck (157229), Zhou Zhemin, Brisse, Sylvain, Harbottle, Heather, John Wain (157211), Weill, FX, Zhou, Z., Weill, François-Xavier, Zhemin Zhou (157214), Heather Harbottle (157226), Vartul Sangal, The S.enterica MLST study group, Gordon Dougan, Hale James L., Hale, J.L., Sangal, V, Achtman, Mark, Sylvain Brisse, Zhou, Zhemin, Harrison, LH, Sangal, V., Nair, Satheesh, Zhemin Zhou, Nair, S., Wain, J., Harrison, Lee H., Uesbeck, A., Bessen, Debra E., Achtman, M., Harrison, L.H., François-Xavier Weill, Vartul Sangal (157216), Mark Achtman, Sylvain Brisse (87594), Dougan, G., Wain, John, Sangal, Vartul, Harbottle, H., Alexandra Uesbeck, Uesbeck Alexandra, Weill, F., Lee H. Harrison (157231), Hale, James L., Lee H Harrison, Heather Harbottle, Hale, James, Dougan Gordon, Krauland, M., Harrison, L., Wain, J, Mark Achtman (126786), James L. Hale (157222), Achtman Mark, Krauland, M.G., Nair Satheesh, François-Xavier Weill (157212), Weill François-Xavier, Harrison, Lee, Mary G Krauland, James L Hale, Dougan, Gordon, Brisse, S, Krauland, Mary, Hale, J., Sangal Vartul, S. Enterica MLST Study Group, Gordon Dougan (30395), Weill, F.X., Uesbeck, A, Satheesh Nair (157213), Krauland, MG, John Wain, Harbottle, H, Harrison Lee H., Krauland Mary G., Dougan, G, Achtman, M, Arias-Pineda, Jesús David, Pitre-Guerrero, Eison Alfredis   +90 more
core   +1 more source

Antioxidant, Anti-Inflammatory, and Anti-Cancer Properties of Amygdalin Extracted from Three Cassava Varieties Cultivated in Benin

Molecules, 2023
Given that cancer is a disease that is rampant in the world and especially in Africa, where the population has enormous difficulty treating it, plants are a safer and less expensive alternative.
Halfane Lehmane, Arnaud N. Kohonou, Atchadé Pascal Tchogou, Radiate Ba, Durand Dah-Nouvlessounon, Oscar Didagbé, Haziz Sina, Maximin Senou, Adolphe Adjanohoun, Lamine Baba-Moussa   +9 more
doaj   +1 more source

Molecular typing of dengue virus type 2 in Brazil [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2003
Strain typing is a critical tool for molecular epidemiological analysis and can provide important information about the spread of dengue viruses. Here, we performed a molecular characterization of DEN-2 viruses isolated in Brazil during 1990-2000 from geographically and temporally distinct areas in order to investigate the genetic distribution of this ...
Miagostovich, Marize P., Sequeira, Patrícia C., Santos, Flávia B. dos, Maia, Amanda, Nogueira, Rita Maria R., Schatzmayr, Hermann G., Harris, Eva, Riley, Lee W.   +7 more
openaire   +5 more sources