Results 141 to 150 of about 1,583,259 (269)

Revisiting low-molecular-weight heparin for venous thromboembolism: from pharmacology to precision dosing and implementation. [PDF]

Front Pharmacol
Zhu S, Ni Q, He J.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Low molecular weight 4,4'-quinocyanines for in vivo NIR-II fluorescence imaging. [PDF]

Npj Imaging
Isuri RK, Hart MC, Adusei-Poku S, Dudek GC, Delikatny EJ, Popov AV.   +5 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Sternal Re-Closure for Refractory Dehiscence Using Ultra-High Molecular Weight Polyethylene Tape. [PDF]

Interdiscip Cardiovasc Thorac Surg
Niki T, Nakahara Y, Iwakura T, Marui A.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Tailored molecular weight hyaluronic acid production by engineered Lactococcus lactis. [PDF]

Microb Cell Fact
Soundiraraj S, Ravishankar N, Jeeva P, Blank LM, Jayaraman G.   +4 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Sonication-Freezing-Assisted Extraction of Chia Seed Mucilage: Functional and Structure-Rheology Relationships and Molecular Weight Determination. [PDF]

Gels
Sanpedro-Díaz M, Medina-Bañuelos EF, Salgado-Cruz MP, Marín-Santibáñez BM, García-Hernández AB, Gómez-Gómez AL, Hernández-Martínez DM.   +6 more
europepmc   +1 more source

Molecular Weight and Molecular Weight Distribution (2)

Sen'i Gakkaishi, 1976
openaire   +2 more sources