Results 201 to 210 of about 3,138,502 (297)

Molecular Design with Artificial Intelligence: Progress and Perspectives for Small Molecules. [PDF]

Chem Rev
Sumita M, Ishida S, Yoshizoe K, Tamura R, Terayama K, Tsuda K.   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Correction: Gas-phase synthesis of the bicyclic silicon tricarbide molecule (c-SiC₃) as a precursor to silicon carbide nanoparticles in space. [PDF]

Chem Sci
Goettl SJ, Fujioka K, Alves MO, Silva MX, Yang Z, Metya S, Medvedkov IA, Sattasathuchana T, Galvão BRL, Sun R, Kaiser RI.   +10 more
europepmc   +1 more source

Shrinking molecules

Journal of Chemical Education, 1977
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

[Retracted] Vascular endothelial growth factor participates in modulating the C6 glioma-induced migration of rat bone marrow-derived mesenchymal stem cells and upregulates their vascular cell adhesion molecule-1 expression. [PDF]

Exp Ther Med
Gao Z, Cheng P, Xue Y, Liu Y.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Water Molecule(s) Inside the Selectivity Filter of Aquaporin 1: A DFT Study. [PDF]

Molecules
Angelova S, Frutos LM, Kircheva N, Zagranyarski Y, Castaño OD, Dudev T.   +5 more
europepmc   +1 more source