Results 211 to 220 of about 3,841,010 (347)

Catalytic in vivo protein knockdown by small-molecule PROTACs.

Nature Chemical Biology, 2015
Daniel P. Bondeson, A. Mareş, I. E. Smith, Eunhwa Ko, Sebastien Campos, Afjal H Miah, K. Mulholland, Natasha Routly, Dennis L. Buckley, J. Gustafson, N. Zinn, P. Grandi, S. Shimamura, G. Bergamini, Maria Faelth-Savitski, M. Bantscheff, Carly S Cox, D. Gordon, Ryan R Willard, J. Flanagan, Linda N. Casillas, B. Votta, W. den Besten, K. Famm, L. Kruidenier, P. Carter, J. Harling, I. Churcher, C. Crews   +28 more
semanticscholar   +1 more source

Direct Proof of the Existence of Metastable Molecules in Active Nitrogen [PDF]

, 1934
Joseph Kaplan
openalex   +1 more source

Generative artificial intelligence based models optimization towards molecule design enhancement. [PDF]

J Cheminform
Khater T, Alkhatib SA, AlShehhi A, Pitsalidis C, Pappa AM, Ngo ST, Chan V, Truong VK.   +7 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

Nature Methods, 2008
K. Neuman, A. Nagy
semanticscholar   +1 more source

Single-Molecule Conductance through Hybrid Radially and Linearly π-Conjugated Macromolecules Reveals an Unusual Intramolecular π-Interaction. [PDF]

Nano Lett
Shi W, Wang M, Venkataraman L, Tovar JD.
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

A practical guide to single-molecule FRET

Nature Methods, 2008
R. Roy, S. Hohng, T. Ha
semanticscholar   +1 more source

LXI. Construction of compound molecules with theoretical atoms, especially the systems of growth of the organic compounds of carbon and hydrogen [PDF]

, 1915
Albert C. Crehore
openalex   +1 more source

CSGL: chemical synthesis graph learning for molecule representation. [PDF]

Bioinformatics
Li A, Casiraghi E, Rousu J.
europepmc   +1 more source