Reverse engineering molecules from fingerprints through deterministic enumeration and generative models. [PDF]
Meyer P +3 more
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Raman identification of single nucleotides flowing through permeable plasmonic films. [PDF]
Khabarov K +15 more
europepmc +1 more source
The Paramagnetism of “Odd Molecules” [PDF]
Nelson W. Taylor, Gilbert N. Lewis
openalex +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Rolling Circle Amplification as a Molecular Tool for Spatially Resolved Signal Amplification in Single Molecule Counting Assay. [PDF]
Park J.
europepmc +1 more source
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
Beili Wu +14 more
semanticscholar +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Design, Synthesis, and Aggregation-Induced Emission Properties of a Novel D-π-A Conjugated Molecule as a Selective Hydrazine Sensor. [PDF]
Cansever O, Yagiz Erdemir G.
europepmc +1 more source

