RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Single-Molecule Electron Transport in Peptoids. [PDF]
Prempin B +7 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Photophysics of Organic Fluorophore Photobluing and Its Applications in Fluorescence and Super-Resolution Microscopy. [PDF]
Son JB +6 more
europepmc +1 more source
Accurate Prediction of pKb in Amines: Validation of the CAM-B3LYP/6-311+G(d,p)/SMD Model. [PDF]
Pezzola S +5 more
europepmc +1 more source
Key contemporary considerations for halogens in drug discovery. [PDF]
Ali S, Zhou J.
europepmc +1 more source
Heteroatomic Andreev Molecule in a Superconducting Island-Double Quantum Dot Hybrid. [PDF]
Kürtössy O +9 more
europepmc +1 more source
How to evaluate aromaticity under pressure? Benzene as a benchmark system. [PDF]
Eeckhoudt J +6 more
europepmc +1 more source
ALDH1 and ALCAM as emerging biomarkers in personalized rectal cancer therapy. [PDF]
Ribas-Filho JM +9 more
europepmc +1 more source

