Results 251 to 260 of about 5,323,640 (377)

Molecular Polarizability under Vibrational Strong Coupling. [PDF]

J Chem Theory Comput
Schnappinger T, Kowalewski M.
europepmc   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Catalytic in vivo protein knockdown by small-molecule PROTACs.

Nature Chemical Biology, 2015
Daniel P. Bondeson, A. Mareş, I. E. Smith, Eunhwa Ko, Sebastien Campos, Afjal H Miah, K. Mulholland, Natasha Routly, Dennis L. Buckley, J. Gustafson, N. Zinn, P. Grandi, S. Shimamura, G. Bergamini, Maria Faelth-Savitski, M. Bantscheff, Carly S Cox, D. Gordon, Ryan R Willard, J. Flanagan, Linda N. Casillas, B. Votta, W. den Besten, K. Famm, L. Kruidenier, P. Carter, J. Harling, I. Churcher, C. Crews   +28 more
semanticscholar   +1 more source

Analytical techniques for nucleic acid and protein detection with single-molecule sensitivity. [PDF]

Exp Mol Med
Shin S, Kim J, Song E, Han S, Hohng S.
europepmc   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Interrelations of Quantum-Mechanical Quantities Concerning Chemical Reactivity of Conjugated Molecules [PDF]

, 1957
Kenichi Fukui, Teijiro Yonezawa, Chikayoshi Nagata   +2 more
openalex   +1 more source

An international dataset on organic molecule concentrations in soil and related kitchen garden crops. [PDF]

Sci Data
Laurent C, Genies L, Bidar G, Ripamonti-Chenot ED, Dumat C, Hulot C, Marot F, Schwartz C, Ouvrard S.   +8 more
europepmc   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

THE ORIENTATION OF MOLECULES IN SURFACES, SURFACE ENERGY, ADSORPTION, AND SURFACE CATALYSIS. V. THE ADHESIONAL WORK BETWEEN ORGANIC LIQUIDS AND WATER.¹ [PDF]

, 1920
William D. Harkins, George L. Clark, Lathrop E. Roberts   +2 more
openalex   +1 more source

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

Nature Methods, 2008
K. Neuman, A. Nagy
semanticscholar   +1 more source