Results 41 to 50 of about 3,841,010 (347)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Forces in Molecules [PDF]

open access: yesPhysical Review, 1939
Formulas have been developed to calculate the forces in a molecular system directly, rather than indirectly through the agency of energy. This permits an independent calculation of the slope of the curves of energy vs. position of the nuclei, and may thus increase the accuracy, or decrease the labor involved in the calculation of these curves.
openaire   +5 more sources

Biology, Bionomics and Molecular Biology of Anopheles sinensis Wiedemann 1828 (Diptera: Culicidae), Main Malaria Vector in China

open access: yesFrontiers in Microbiology, 2017
China has set a goal to eliminate all malaria in the country by 2020, but it is unclear if current understanding of malaria vectors and transmission is sufficient to achieve this objective.
Xinyu Feng   +41 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Hadronic molecules [PDF]

open access: yesReviews of Modern Physics, 2018
Corrected several entries in Table VI for the contact terms for the S-wave interactions between the spin multiplets of D1 and Dbar; 67 pages, 23 ...
Guo, Feng-Kun   +5 more
openaire   +3 more sources

Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire

open access: yesCommunications Biology, 2022
The authors developed a methodology for bulk enrichment of antigen-specific B cells to improve the diversity of antibody sequences and increase the number of functional antigen-specific antibodies coming from different antibody generation platforms.
Ankit Mahendra   +20 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

α-Molecules

open access: yesApplied and Computational Harmonic Analysis, 2016
Within the area of applied harmonic analysis, various multiscale systems such as wavelets, ridgelets, curvelets, and shearlets have been introduced and successfully applied. The key property of each of those systems are their (optimal) approximation properties in terms of the decay of the L2-error of the best N-term approximation for a certain class of
Grohs, Philipp   +3 more
openaire   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

The Expression of Myoz1 and ApoB is Positively Correlated with Meat Quality of Broiler Chicken

open access: yesVeterinary Medicine International, 2022
Broiler chicken (Gallus gallus) is a source of animal protein with a high nutritional content. The purpose of this study was to evaluate the quality of broiler chicken meat (Gallus gallus) by analyzing its nutritional value, genetic profile, and protein ...
Fatchiyah Fatchiyah   +7 more
doaj   +1 more source

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