Results 211 to 220 of about 104,482 (285)

Lead radionuclides for theranostic applications in nuclear medicine: from atom to bedside. [PDF]

Theranostics
Berckmans Y, Kleynhans J, Van Mechelen S, Goffin K, Baete K, Koole M, Coosemans A, Cocolios TE, Deroose CM, Seimbille Y, Cleeren F.   +10 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Unraveling Torsional Preferences: Comparative Analysis of Torsion Motif Torsional-Angle Distributions across Different Environments. [PDF]

J Chem Inf Model
Braun J, Katzberger P, Landrum GA, Lamei D, Riniker S.   +4 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Transport and Reaction of Electrons and Molecules in Solid Electrolyte Interphases formed at Different Electrode Potentials: A Combined Experimental and Modeling Approach. [PDF]

ChemSusChem
Krauss FT, Duncker A, Roling B.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1. [PDF]

Commun Chem
Doppler D, Grieco A, Koh D, Manna A, Ansari A, Alvarez R, Karpos K, Le H, Sonker M, Ketawala GK, Mahmud S, Quereda-Moraleda I, Sen S, Pey AL, Letrun R, Dörner K, Koliyadu JCP, de Wijn R, Bielecki J, Han H, Kim C, Koua FHM, Round A, Sarma A, Sato T, Schmidt C, Vakili M, Zabelskii D, Bean R, Mancuso AP, Schulz J, Fromme R, Medina M, Grant TD, Fromme P, Kirian RA, Botha S, Manuel Martin-Garcia J, Ros A.   +38 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Transfer learning from custom-tailored virtual molecular databases to real-world organic photosensitizers for catalytic activity prediction. [PDF]

Commun Chem
Noto N, Nagano T, Fujinami M, Kojima R, Saito S.   +4 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source