Results 231 to 240 of about 104,482 (285)

A novel device for in-situ on-demand hydrogen sulfide generation and delivery to increase tissue perfusion to chronic wounds. [PDF]

J Biol Eng
Justus M, Friedrichsen D, Brooks B, Silaski G, Beckius R, Massie P, Pace C, Kulkarni D, Self T, Mattox M, Bray J, Risotto-Urbanowicz E, Iturralde-Carillo A, Marek J, Coffman B, Heaps C, Ferguson H, Shekarriz R, Kanagy N, Clark R.   +19 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Foundation and Multimodal Models for Drug Discovery in Molecular Informatics: Principles, Evaluation, and Practical Guidance. [PDF]

Mol Inform
Pastore EP, De Rango F.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Toothbrush-Driven Handheld Droplet Generator for Digital LAMP and Rapid CFU Assays. [PDF]

Biosensors (Basel)
Lai X, Zhu Y, Yang M, Wang X.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Rapid Generation of Transition-State Conformer Ensembles via Constrained Distance Geometry. [PDF]

J Chem Inf Model
Schmid SP, Seng H, Kläy T, Jorner K.
europepmc   +1 more source

Generative artificial intelligence based models optimization towards molecule design enhancement. [PDF]

J Cheminform
Khater T, Alkhatib SA, AlShehhi A, Pitsalidis C, Pappa AM, Ngo ST, Chan V, Truong VK.   +7 more
europepmc   +1 more source

Exploring Optimized Organic Fluorophore Search through Experimental Data-Driven Adaptive β‑VAE. [PDF]

JACS Au
Xu Y, Luo Y, Li B, Jiang W, Zhang J, Wei J, Bai H, Wang Z, Ge J, Lin R, Mi Z, Zhang H, Tang Y, Jones MS, Li X, Zhang JZH, Ju CW.   +16 more
europepmc   +1 more source

Selection criteria for foaming agent and mechanical performance evaluation of conditioned soil for EPB shield tunneling in water-rich sand strata. [PDF]

Sci Rep
Zhou Y, Zhu B, Luo R, Yu J, Yang Q, Nimbalkar S.   +5 more
europepmc   +1 more source