Results 111 to 120 of about 386,582 (351)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Early hydration and mechanical performance of composited cementitious system prepared from high temperature calcined molybdenum tailings

open access: yesCase Studies in Construction Materials
To improve the recycling of solid waste and achieve the secondary utilization of waste resources, this study investigates the preparation of molybdenum tailings composited binders by high temperature calcination using molybdenum tailings, limestone ...
Jun Li   +10 more
doaj   +1 more source

Bend transition temperature of arc-cast molybdenum and molybdenum - 0.5-percent- titanium sheet in worked, recrystallized, and welded conditions [PDF]

open access: yes
Bend transition temperature of arc-cast worked, recrystallized, and welded molybdenum and molybdenum-titanium alloy ...
Sinclair, J. H.
core   +1 more source

Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice

open access: yesNature Communications, 2018
Acute kidney injury (AKI) is a common reactive oxygen species (ROS)-related renal disease that causes numerous deaths annually, yet only supportive treatment is currently available in the clinics.
Dalong Ni   +13 more
semanticscholar   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Molybdenum in natural waters: A review of occurrence, distributions and controls

open access: yes, 2017
Molybdenum is an essential trace element for human, animal and plant health and has played an important part in the evolution of life on earth. Nonetheless, exposure to the element can be harmful and although the evidence for symptoms in humans is sparse,
P. Smedley, D. Kinniburgh
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Development and Utilization Status and the Future Demand Forecast of Molybdenum Resources in China

open access: yesKuangchan zonghe liyong
This is an article in the field of mining engineering. This article analyzes the present situation of molybdenum resource exploitation and utilization in China, and predicts the future demand formolybdenum resource in China.
Xiu WANG   +4 more
doaj   +1 more source

Development of aircraft brake materials [PDF]

open access: yes
The requirements of brake materials were outlined and a survey made to select materials to meet the needs of high temperature brakes. A number of metals and ceramic materials were selected and evaluated in sliding tests which simulated aircraft braking ...
Ho, T. L., Peterson, M. B.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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