Results 131 to 140 of about 5,659 (287)
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
Incorporating mineral admixtures is essential to modulate the fresh and hardened properties of self-consolidating concrete (SCC). This study introduced waste molybdenum tailings (MT) as a novel mineral admixture, substituting fly ash in SCC for the first
Luo Tao +7 more
doaj +1 more source
The Sorsky Mining Complex molybdenum ores flotation tailings recycling in cellular thermalinsulating- structural ceramics production [PDF]
Э. М. Никифорова +2 more
openalex +1 more source
Refining the site conceptual model at a former uranium mill site in Riverton, Wyoming, USA [PDF]
core +1 more source
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang +9 more
wiley +1 more source
EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv +8 more
wiley +1 more source
Investigation of unfired Bricks Prepared by Shangluo Molybdenum tailings [PDF]
Chunsheng Zhou +4 more
openalex +1 more source
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian +12 more
wiley +1 more source

