Results 31 to 40 of about 107,221 (240)

Experimental Research on the Compression Property of Geopolymer Concrete with Molybdenum Tailings as a Building Material

Buildings, 2022
This paper experimentally studied the effects of different molybdenum tailings (MoT) content, standard curing and 60 °C water curing conditions on the compressive strength of fly ash-based geopolymers at different ages.
Ming Sun, Yin Fu, Weixin Wang, Youzhi Yang, An Wang   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Enrichment of manufactured waste at the AMMC copper processing factory in Uzbekistan [PDF]

E3S Web of Conferences
This article is devoted to the additional extraction of valuable components from the waste tailings of the AMMC copper processing plant. The mineral composition of the waste tailings of the CCP is mainly represented by quartz, feldspars, sericites and ...
Makhmarezhabov Dilmurod, Bekpulatov Javlon, Salizhanova Gulnarakhon, Amindjanova Sevara, Abdurasulova Zarina, Rasulova Shakhnoza   +5 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Preparation and Hydration Mechanism of Molybdenum Tailings Coupled with Slag Powder Cement-based Materials

Kuangchan zonghe liyong
[Objective] In order to improve the utilization efficiency of tailings and reduce the environmental problems caused by tailings storage, this article focuses on molybdenum tailings as the main research object, and couples molybdenum tailings with slag ...
Guangtian ZHANG, Yanjia ZHANG, Shuanggen LIN, Guangwei HE   +3 more
doaj   +1 more source

The Experimental Research on the Sedimentation Performance of one Molybdenum Ore Flotation Tailings

, 2011
This paper adopts sedimentation experiment to study the sedimentation process of one molybdenum ore flotation tailings and to investigate the effects of lime and sodium silicate on sedimentation performance of tailings.
Jun Qiu, Xian Jun Lu, Lin Li, Peng Li
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Preparation of Glass-Ceramics Using Molybdenum Tailings

, 2011
In order to utilization the molybdenum tailings which be deposited in large quantities. Test used it to prepare glass-ceramics as main raw material, TiO2 as nucleation agents and CaO-Al2O3-SiO2 system and wollastonite as the principal crystalline phase ...
Ru Wang, Jin Rui Zhang
core   +1 more source