Results 41 to 50 of about 5,582 (291)

Effect of recycled molybdenum tailings on mechanical properties of ultra-high-performance concrete

Frontiers in Materials
This paper presents experimental studies on mechanical properties and micro-structures of ultra-high performance concrete (UHPC) made of recycled molybdenum tailings.
Xin Li, Cun-Xiang Liu, Xin-Yu Zhao, Xin-Yu Zhao, Shao-Bo Kang, Shao-Bo Kang   +5 more
doaj   +1 more source

Enrichment of manufactured waste at the AMMC copper processing factory in Uzbekistan [PDF]

E3S Web of Conferences
This article is devoted to the additional extraction of valuable components from the waste tailings of the AMMC copper processing plant. The mineral composition of the waste tailings of the CCP is mainly represented by quartz, feldspars, sericites and ...
Makhmarezhabov Dilmurod, Bekpulatov Javlon, Salizhanova Gulnarakhon, Amindjanova Sevara, Abdurasulova Zarina, Rasulova Shakhnoza   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A new family of periplasmic-binding proteins that sense arsenic oxyanions [PDF]

, 2018
Arsenic contamination of drinking water affects more than 140 million people worldwide. While toxic to humans, inorganic forms of arsenic (arsenite and arsenate), can be used as energy sources for microbial respiration. AioX and its orthologues (ArxX and
AJ McCoy, C Baraquet, C Jourlin, CN Pace, D Malasarn, D Slyemi, DL Correll, DR Kashyap, E Afkar, E Lebrun, G Liu, GD Duyne Van, GH Scheepers, GL Anderson, GN Murshudov, H Edelhoch, I Alicea, J Andres, JM Santini, JM Santini, JM Santini, K Fukami-Kobayashi, K Kurashima-Ito, K Tamura, K Zargar, KH Johannesson, KU Kjeldsen, L Ferrières, LS Jenkins, M Meyer, MB Neiditch, MD Winn, P Emsley, RC Edgar, RS Oremland, S Duval, S Koechler, S Sardiwal, SF Altschul, T Krafft, TH Osborne, TP Warelow, WL DeLano, X Chen   +43 more
core   +5 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Experimental Study on Axial Compression Behavior of Molybdenum Tailings Concrete Column Confined by GFRP

Buildings
To promote the application of molybdenum tailings as the fine aggregate in concrete in construction engineering and verify the feasibility of fiber-reinforced polymer (FRP) material for strengthening molybdenum tailings concrete columns, this study takes
Jian Yuan, Xin Zhao, Lianmin Tian, Zhaolong Hou, Yunfeng Pan, Jun He   +5 more
doaj   +1 more source

The Effects of Surface Disturbances on the Leaching of Heavy Metals [PDF]

, 1987
The harmful effects of heavy metal contamination of surface waters impacted by gold mining activity are well documented. An examination was conducted on the effects of surface disturbances in Wade Creek on the concentrations of heavy metals in ...
Brown, Edward J., Dixson, David P.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Molybdenum supplementation of fat-tailed ewes diets in an arid region

Online Journal of Animal and Feed Research, 2022
The study aimed to establish the normal molybdenum requirements for open ewes of meat-and-fat breeds in arid climatic conditions. The study was carried out in the production conditions of the Buddha farm of the Republic of Kalmykia (Russia). The norm has been established based on a detailed study of the molybdenum content in organs and tissues and the ...
Djunaydi Sharamazanovich GAYIRBEGOV, Dmitry Borisovich MANDZHIEV, Tseden Badmaevich TYURBEEV   +2 more
openaire   +1 more source