Results 101 to 110 of about 145,608 (302)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Moment generating function of a first hitting place for the integrated Ornstein-Uhlenbeck process
, 1989 We consider the two-dimensional process (x(t),y(t)), where y(t)=dx(t)/dt is an Ornstein-Uhlenbeck process, Let T be the smallest t for which y(t) = υ.
Lefebvre, Mario
core +1 more source
Moments by Integrating the Moment-Generating Function
We introduce a novel method for obtaining a wide variety of moments of any random variable with a well-defined moment-generating function (MGF). We derive new expressions for fractional moments and fractional absolute moments, both central and non-central moments.
Hansen, Peter Reinhard, Tong, Chen
openaire +2 more sources
Characterizing Exponential Family Distributions by Moment Generating Functions
The Annals of Statistics, 1975 It is shown that if $\mathbf{T}$ has an unknown exponential family distribution with natural parameter $\mathbf{\theta}$, then $\mathbf{G(\theta)} = \mathbf{ET}$ uniquely specifies the moment generating function. The converse is proved, namely, if $\{\mathbf{T_\theta}\}$ is a family of random variables with moment generating functions of a certain form,
openaire +2 more sources
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
, 2007 In this paper tests of hypothesis are constructed for the family of skew normal distributions. The proposed tests utilize the fact that the moment generating function of the skew normal variable satisfies a simple differential equation.
Meintanis, S.G.
core
New Lifetime Alpha Power Exponential Weibull Distribution: Structure and Properties
Ibn Al-Haitham Journal for Pure and Applied SciencesIn statistics theory, adding a new parameter is considered one of the important things that help in producing statistical distributions more flexible and appropriate in data analysis.
Hiba Mahdi Saleh +2 more
doaj +1 more source