Results 71 to 80 of about 6,770,320 (292)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Saddlepoint Approximation to a Distribution-Free Test for Stochastic Ordering in the Competing Risks Model

Revstat Statistical Journal, 2009
The approximation for the distribution function of a test statistic is extremely important in statistics. A distribution-free test for stochastic ordering in the competing risks model has been proposed by Bagai et al. (1989).
Hidetoshi Murakami
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Performance Analysis of HARQ for Moment Generating Function in Nakagami-m Fading Channels

工程科学与技术, 2014
:A joint optimization algorithm which combines M-QAM with HARQ protocol is proposed for the multi-branch two-top cooperation diversity system to minimize the symbol error rate (SER) and maximize the throughput. Using moment generating function (MGF), the
陈昌川, 饶毓, 赵超莹
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

PEMBUKTIAN KEKONVERGENAN DISTRIBUSI SAMPLING KE DISTRIBUSI NORMAL MENGGUNAKAN MOMENT GENERATING FUNCTION [PDF]

, 2016
Kekonvergenan distribusi sampling yang dimaksud dalam skripsi ini adalah kekonvergenan dari distribusi sampling untuk mean atau rata – rata. Permasalahan yang diangkat yaitu membuktikan kekonvergenan distribusi sampling ke distribusi normal menggunakan ...
ALIF ANGGRAENI, DINA
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Mathematical modeling for Human Immunodeficiency Virus (HIV) transmission using generating function approach [PDF]

, 2015
This study is concerned with the mathematical modeling for human immunodeficiency virus (HIV) transmission epidemics. The mathematical models are specified by stochastic differential equations that are solved by use of Generating Functions (GF ...
Olowofeso, Olorunsola E., Waema, Rachel
core