Results 101 to 110 of about 79,797 (290)
A Moment Map for the Space of Maps to a Balanced Manifold [PDF]
, 2023 Dan Popovici, Luis Ugarte
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Harmonic morphisms and moment maps on hyper-Kähler manifolds [PDF]
, 2013 M. Benyounes, E. Loubeau, Radu Pantilie
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Large deviations, moment estimates and almost sure invariance principles for skew products with mixing base maps and expanding on the average fibers [PDF]
, 2021 Yeor Hafouta
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, 1997 Aspects of Poisson-Lie T-duality are reviewed in more algebraic way than in our, rather geometric, previous papers. As a new result, a moment map is constructed for the Poisson-Lie symmetry of the system consisting of open strings propagating in a Poisson-Lie group manifold.
Klimcik, C., Severa, P.
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FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Isotropic maps and moment map flow
We consider the moduli space of isotropic maps from a closed surface $Σ$ to a symplectic affine space and construct a Kähler moment map geometry, on a space of differential forms on $Σ$, such that the isotropic maps correspond to certain zeroes of the moment map.
Jauberteau, François, Rollin, Yann
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source