Results 71 to 80 of about 48,655 (263)

Matching conditions for values of characteristic oblique derivative at the end of a string, initial data and right-hand side of the wave equation

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2020
Sufficient matching conditions the time-dependent characteristic first derivatives in the boundary mode with the initial conditions and the more general vibration equation of a semi-bounded string are derived in the sets of solutions of all higher order ...
Ekaterina V. Ustilko   +1 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Multi-spectral remote sensing image fusion method based on gradient moment matching

open access: yesSystems and Soft Computing
Image fusion is a popular research direction in the field of computer vision. Traditional image fusion algorithms can achieve good results in fusing grayscale images, but it is difficult to achieve ideal results in processing multi-spectral images.
Haiying Fan, Gonghuai Wei
doaj   +1 more source

Dynamic asymmetric assignment problem in open multi-agent systems

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2020
The purpose of the work is to develop models and algorithms for optimizing matching in dynamically generated graphs of asymmetric relations in coordinated open systems of interacting agents with centralized and collective control.
M. P. Revotjuk   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The moments of matched and mismatched hidden Markov models [PDF]

open access: yesIEEE Transactions on Acoustics, Speech, and Signal Processing, 1990
An algorithm for computing the moments of matched and mismatched hidden Markov models (HMMs) from their defining parameters is presented. The algorithm is an extension of the usual forward-backward linear recursion. The algorithm computes the joint moments of the posterior likelihood functions (i.e.
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Signal Generator Agnostic Moment Matching

open access: yesIEEE Transactions on Automatic Control
We study the model-reduction problem by moment matching for linear and nonlinear systems in a data-driven setting. We show that reduced-order models can be directly computed from input–output data without requiring knowledge of the structure of the signal generator or its internal state.
Debraj Bhattacharjee   +2 more
openaire   +2 more sources

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