Results 91 to 100 of about 141,189 (298)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

ON NATURAL FLEXURAL VIBRATIONS IN A STEPWISE CANTILEVER BEAM WITH AN ATTACHED DISTRIBUTED MASS

Structural Mechanics of Engineering Constructions and Buildings, 2013
Consideration is given to natural flexural vibrations in a stepwise cantilever beam with an attached distributed mass. The research shows that an increase in the initial coordinate of the distributed mass results in greater natural vibration frequencies ...
A G Khakimov
doaj  

The Eckart frame Hamiltonians in the three-body problem

, 2013
The Eckart frame is used to separate out the collective rotations in the quantum three-body problem. Explicit expressions for the corresponding rotational and vibro-rotational (i.e. Coriolis) Hamiltonians are derived.
Meremianin, A. V.
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

TWO-MASS MODEL OF THE SYSTEM OF FORCE GYROSCOPIC STABILIZATION

Авіаційно-космічна техніка та технологія, 2017
The mechanical system of the gyro stabilization device on one axle, consisting of a stabilizing engine and a hinged frame, has been investigated using a two model that adopts as the first mass a stabilizing engine, аnd as an inferred mass, the gyroscope ...
Энвер Тапдыг Газарханов, Тогрул Иса Каримли, Васиф Айдын Нейматов   +2 more
doaj   +1 more source

Rotating Neutron Stars in a Chiral SU(3) Model

, 2002
We study the properties of rotating neutron stars within a generalized chiral SU(3)-flavor model. The influence of the rotation on the inner structure and the hyperon matter content of the star is discussed.
D Zschiesche, Glendenning N K, Glendenning N K, Lyne A G, Manchester R, Oppenheimer J R, Papazoglou P, S Schramm, Schechter J, Schramm S, Tolman R C, Weber F   +11 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Using interactive methods for teaching principal axes and moments of inertia [PDF]

, 2010
Engineering analysis and design often uses properties of plane sections in calculations. For example, in stress analysis of a beam under bending and torsional loads, you use the cross-sectional properties to determine the stress and displacement ...
Carbonell Padrino, Maria Victoria, Florez Garcia, Mercedes, Martinez Ramirez, Elvira   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source