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The Role of Momordica charantia in Resisting Obesity [PDF]
International Journal of Environmental Research and Public Health, 2019 Momordica charantia (M. charantia), commonly known as bitter gourd, bitter melon, kugua, balsam pear, or karela, is a tropical and sub-tropical vine belonging to the Cucurbitaceae family. It has been used to treat a variety of diseases in the traditional medicine of China, India, and Sri Lanka.
Sangho Moon, Eun-Kyung Kim, Meiqi Fan
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Momordica charantia L. Cucurbitaceae
2020It is a climbing, nearly or quite smooth, annual vine that is widely grown in Asia (especially Indian subcontinent), Africa, and in central Europe. Hindu physicians in India used the whole plant combined with cinnamon, long pepper, rice and the oil of Hydnocarpus wightiana as an external application in scabies and other skin diseases. Fruits and leaves
Narel Y. Paniagua-Zambrana +2 more
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Antimutagens from Momordica charantia
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1990The antimutagenic principle of the green fruits of Momordica charantia was shown by the micronucleus test to be an intractable mixture of novel acylglucosylsterols. The antimutagens were extracted from the green fruits with ethanol and isolated from the bioactive petroleum ether and carbon tetrachloride extracts by repeated and sequential flash column ...
A P, Guevara +3 more
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Momordica charantia, a Nutraceutical Approach for Inflammatory Related Diseases [PDF]
Frontiers in Pharmacology, 2019 Momordica charantia, commonly called bitter melon, is a plant belonging to Cucurbitaceae family known for centuries for its pharmacological activities, and nutritional properties. Due to the presence of many bioactive compounds, some of which possess potent biological actions, this plant is used in folk medicine all over the world for the treatment of ...
Letizia Polito +2 more
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The Antigluconeogenic Activity of Cucurbitacins from Momordica charantia
Planta Medica, 2015Five new cucurbitacins, kuguacins II-VI (1-5), along with five known analogues (6-10), were obtained from the fruit of Momordica charantia. Structures of the new compounds were elucidated as 5β,19-epoxycucurbit-23-en-7-on-3β,25-diol (1), 5β,19-epoxycucurbit-7,23-dion-3β,25-diol (2), 5β,19-epoxycucurbit-6-en-19,23-dion-3β,25-diol (3), 5β,19-epoxy-23,24 ...
Mingjin Xie +2 more
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Extra-pancreatic effects of Momordica charantia in rats
Journal of Ethnopharmacology, 1986The extra pancreatic effects of the oral hypoglycaemic plant Momordica charantia have been investigated in rats. It was found that the fruit juice of this plant caused an increased glucose uptake by tissues in vitro without concomitant increase of tissue respiration.
J, Welihinda, E H, Karunanayake
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Hypoglycaemic Effect ofMomordica charantiaExtracts
Planta Medica, 1990The hypoglycaemic effect of orally administered extracts of fruits of cultivated Momordica charantia (karela) was examined in normal and streptozotocin diabetic mice. In normal mice, an aqueous extract (A) lowered the glycaemic response to both oral and intraperitoneal glucose, without altering the insulin response.
C, Day +3 more
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Insulin-like molecules in Momordica charantia seeds
Journal of Ethnopharmacology, 1986Decorticated Momordica charantia seeds were extracted and processed by a method which was developed originally for the purification of insect and annelid insulins. Essentially, the method entailed HCl--ethanol extraction, neutralization with NH4OH, gel filtration on Sephadex G-50, ion exchange chromatography on CM Sepharose CL-6B and desalting on ...
T B, Ng, C M, Wong, W W, Li, H W, Yeung
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Pharmacodynamic interaction of Momordica charantia with rosiglitazone in rats
Chemico-Biological Interactions, 2009The present study was undertaken to determine the interaction of rosiglitazone, a PPAR-gamma agonist with methanolic extract of Momordica charantia L (MC), an herbal drug used widely as an antidiabetic agent. The pharmacodynamic interaction was evaluated in oral glucose tolerance test, streptozotocin (STZ) induced diabetes in adult rats and STZ induced
Susan Nancy, Nivitabishekam +2 more
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Effect of Momordica charantia on key hepatic enzymes
Journal of Ethnopharmacology, 1994The effect of Momordica charantia on certain key hepatic enzymes was investigated using male Sprague-Dawley rats as the animal model. Fruit juice and seed extract of Momordica charantia were administered orally at a daily dose of 1 ml/100 g body weight for 30 days under light ether anaesthesia while the control group received equivalent amounts of ...
K H, Tennekoon +4 more
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