Results 41 to 50 of about 21,025 (223)

Low doses of monensin for lambs fed diets containing high level of ground flint corn

Scientia Agricola, 2020
Two experiments were proposed to evaluate the addition of monensin for lambs fed diets containing a high level of mature ground flint corn. The experimental diets were as follows: no inclusion of monensin (M0) and inclusion of 8 (M8), 16 (M16) and 24 mg ...
Daniel Montanher Polizel, André Storti Martins, Alexandre Arantes Miszura, Marcos Vinícius de Castro Ferraz Júnior, Analisa Vasques Bertoloni, Gabriela Bagio Oliveira, José Paulo Roman Barroso, Evandro Maia Ferreira, Alexandre Vaz Pires   +8 more
doaj   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Mechanisms involved in serum-dependent inactivation of the immunotoxin enhancers monensin and carrier-protein-monensin

, 1994
The immunotoxin-enhancing properties of monensin and of human-serum-albumin-monensin conjugates are severely impaired in the presence of human serum. In this study we have therefore investigated the interaction between serum proteins and monensin leading
Antonia FRANCESCHI, TRIDENTE, Giuseppe, Marcella PASTI, COLOMBATTI, Marco, Carola CANDIANI, F. Dosio, Roberto CHIGNOLA, C. Anselmi, Cristina ANSELMI, C. Candiani, M. Pasti, Marco COLOMBATTI, A. Franceschi, Giuseppe TRIDENTE, CHIGNOLA, Roberto, Franco DOSIO   +15 more
core   +1 more source

Altered protozoan and bacterial communities and survival of Escherichia coli O157:H7 in monensin-treated wastewater from a dairy lagoon.

PLoS ONE, 2013
Surviving predation is a fitness trait of Escherichia coli O157:H7 (EcO157) that provides ample time for the pathogen to be transported from reservoirs (e.g. dairies and feedlots) to farm produce grown in proximity.
Subbarao V Ravva, Chester Z Sarreal, Robert E Mandrell   +2 more
doaj   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

The use of fish meal and monensin as supplements to grass silage and their effect on body composition changes in steers from 5 months of age to slaughter

, 1992
Fish meal and monensin, as supplements to grass silage, were offered either separately or together to Friesian steers from 5 to 9 months of age (period 1).
Baker, R. D., M. J. Gibb, R. D. Baker, Gibb, M. J.   +3 more
core   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

A study of antibody secretion from hybridoma cells [PDF]

, 1988
The secretion of monoclonal antibody in both batch and continuous cultures was studied. It was found that when hybridoma cells were continuously cultivated in a simple lab scale fermenter, they secreted less antibody than cells grown in stationary ...
Holland, P.N.
core  

Monensin-ruokintakoe kasvavilla sonneilla

, 1981
The effect of monensin ongrowth and feed utilization was studied in male calves of milk breeds, mainly Ayrshire. After weaning they were kept in an indicated loose-housing type shed divided into four strawbedded pens.
Tuori, Mikko, Syrjälä-Qvist, Liisa
core   +1 more source