Results 41 to 50 of about 22,788 (224)

CYTOTOXICITY, BIOCHEMICAL EFFECT AND ENVIRONMENTAL IMPACT OF MONENSIN ON DAIRY CATTLE [PDF]

Assiut Veterinary Medical Journal, 2015
Rumensin (monensin) is the first ionophore to be approved by the Food and Drug Administration (FDA) for increased milk production efficiency. Monensin treatment at dose of 10 gm /ton in total mixed ration lead to increase both milk production and body ...
ELALFY MAHMOUD, ABDALLAH AHMED ABDNASER, SLEEM RADWAN FATHY   +2 more
doaj   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Effects of Bacillus licheniformis fermentation extract fed alone or with monensin on production performance and feed efficiency of dairy cows

Journal of Dairy Science
: The study objective was to investigate the impact of monensin and a fermentation extract derived from Bacillus licheniformis–derived fermentation extracts (BLFE) when fed alone or in combination on production performance and feed efficiency in ...
S.L. Rigert, P. Hartoonian, S.E. Omale, S. Rodriguez-Jimenez, C.M.K. Bradley, E.A. Horst, S.K. Kvidera, A.W. Holloway, L.H. Baumgard, J.A.D.R.N. Appuhamy   +9 more
doaj   +1 more source

Evaluation of yeast-based additives, as an alternative to ionophores, on rumen fermentation of ruminant diets using an in vitro gas production system

Frontiers in Animal Science, 2023
IntroductionThe study aimed to assess yeast-based additives' effects, as monensin alternatives, on rumen fermentation parameters, greenhouse gas emissions, and ruminal kinetics of ruminant diets using an in vitro system. Three experiments were conducted,
Amanda Regina Cagliari, Elaine Magnani, Fernanda Rigon, Kalista Eloisa Loregian, Kalista Eloisa Loregian, Ana Claudia Casagrande, Bruna Roberta Amâncio, Juliana Bueno da Silva, Veronica Lisboa Santos, Marcos Inácio Marcondes, Eduardo Marostegan Paula, Pedro Del Bianco Benedeti, Renata Helena Branco   +12 more
doaj   +1 more source

Monensin induces secretory granule-mediated cell death in eosinophils

, 2023
Background: Eosinophils contribute to the pathology of several types of disorders, in particular of allergic nature, and strategies to limit their actions are therefore warranted.
Mirjana Grujic, Grujic, Mirjana, Melo, Fabio R.,, Asp, Elin, Maria Lampinen, Vraila, Marianthi, Melo, Fabio R., Rollman, Ola, Pejler, Gunnar,, Grujic, Mirjana,, Rollman, Ola,, Fabio Rabelo Melo, Ola Rollman, Pejler, Gunnar, Lampinen, Maria,, Elin Asp, Lampinen, Maria, Marianthi Vraila, Asp, Elin,, Gunnar Pejler, Vraila, Marianthi,   +20 more
core   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Low doses of monensin for lambs fed diets containing high level of ground flint corn

Scientia Agricola, 2020
Two experiments were proposed to evaluate the addition of monensin for lambs fed diets containing a high level of mature ground flint corn. The experimental diets were as follows: no inclusion of monensin (M0) and inclusion of 8 (M8), 16 (M16) and 24 mg ...
Daniel Montanher Polizel, André Storti Martins, Alexandre Arantes Miszura, Marcos Vinícius de Castro Ferraz Júnior, Analisa Vasques Bertoloni, Gabriela Bagio Oliveira, José Paulo Roman Barroso, Evandro Maia Ferreira, Alexandre Vaz Pires   +8 more
doaj   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source

A study of antibody secretion from hybridoma cells [PDF]

, 1988
The secretion of monoclonal antibody in both batch and continuous cultures was studied. It was found that when hybridoma cells were continuously cultivated in a simple lab scale fermenter, they secreted less antibody than cells grown in stationary ...
Holland, P.N.
core  

Electrogenic and nonelectrogenic ion fluxes across lipid and mitochondrial membranes mediated by monensin and monensin ethyl ester [PDF]

, 2015
Monensin is a carrier of cations through lipid membranes capable of exchanging sodium (potassium) cations for protons by an electroneutral mechanism, whereas its ethyl ester derivative ethyl-monensin is supposed to transport sodium (potassium) cations in
Antonenko, Yuri N., Huczyński, Adam, Rokitskaya, Tatyana I.   +2 more
core   +1 more source