Results 81 to 90 of about 34,317 (228)

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

Regulatory Patterns of Crp on Monensin Biosynthesis in Streptomyces cinnamonensis

Microorganisms, 2020
Monensin, produced by Streptomyces cinnamonensis, is a polyether ionophore antibiotic widely used as a coccidiostat and a growth-promoting agent in agricultural industry.
Chun-Yan Lin, Yue Zhang, Ji-Hua Wu, Rong-Hui Xie, Jianjun Qiao, Guang-Rong Zhao   +5 more
doaj   +1 more source

Microbiology and cell biology of the interaction between Listeria monocytogenes and Acanthamoeba spp. [PDF]

, 2007
L. monocytogenes is ubiquitous in environment and can grow and survive in a wide range of environmental conditions. It contaminates foods via raw materials or food processing environments. However, the current knowledge of its ecology and in particular,
Akya, Alisha
core   +1 more source

The RNA‐ and DNA‐Binding Protein Y‐Box Binding Protein 1 (YB‐1) Regulates iNKT Cell Development

European Journal of Immunology, Volume 56, Issue 5, May 2026.
YB‐1 is essential for invariant NKT cell development, integrating TCR, co‐stimulatory, and IL‐15 signaling to control maturation, subset differentiation, and survival. Its loss at the double‐positive thymocyte stage causes ∼80% iNKT cell depletion, maturation arrest, impaired cytokine production, and increased apoptosis.
Silvia Schulze, Laura Knop, Nouria Jantz‐Naeem, Vladyslava Dovhan, Stephan Fricke, Sascha Kahlfuß, Thomas Schüler, Ursula Bommhardt   +7 more
wiley   +1 more source

Effects of Beet‐Vinasse (Condensed Molasses Soluble) Addition on the Performance, Milk Fatty Acid Profile, Digestibility, Blood Parameters, and Ruminal Fermentation of Early Lactating Holstein Cows

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Vinasse supplementation at 1.5%–3% enhances nutrient digestibility, ruminal fermentation and production efficiency in early‐lactating Holstein cows. However, without rumen microbial or immune response data, long‐term safety and efficacy require further study.
A. Rahimi, F. Fatehi, H. Rafiee, A. Kahyani   +3 more
wiley   +1 more source

Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: Cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells [PDF]

, 2006
Bovine papillomaviruses (BPVs) are oncogenic viruses. In cattle, BPV-1/2 is associated with urinary bladder cancer and BPV-4 with upper GI tract cancer. BPV E5 is a small hydrophobic protein localised in the endoplasmic reticulum (ER) and Golgi apparatus
Anderson, Araibi, Ashrafi, Ashrafi, Barbara Marchetti, Brad Ozanne, Burnett, Campo, Carragher, DiMaio, Emmanuella Tsirimonaki, Faccini, Fackler, Frame, Frame, Frame, Frame, G. Hossein Ashrafi, Geiger, Hennigan, Jackson, Jaggar, Jarrett, Kasper, Lu, Lynn McGarry, M. Saveria Campo, Marchetti, Nobes, Nunbhakdi-Craig, O’Brien, O’Brien, O’Brien, Pennie, Robina Ullah, Schapiro, Schiller, Scott, Suprynowicz, zur Hausen   +39 more
core   +1 more source

Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis

The FEBS Journal, Volume 293, Issue 10, Page 2845-2861, May 2026.
The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe, Johannes Woelk, Julia Benz, Sarah Spoeck, William J. Olson, Andreas Villunger, Natascha Hermann‐Kleiter, Verena Labi   +7 more
wiley   +1 more source

Occurrence and transformation of veterinary pharmaceuticals and biocides in manure: a literature review [PDF]

, 2016
The spread of veterinary medicinal products (VMPs) and biocides via manure onto agriculturally used areas represents a very important emission into the environment for these product groups.
Berkner, Silvia, Düring, Rolf-Alexander, Junker, Thomas, Konradi, Sabine, Schwarz, Lisa, Wohde, Manuel   +5 more
core   +1 more source

Assessment of the application for modification of the terms of the authorisation of the feed additive consisting of Bacillus velezensis ATCC PTA‐6737 (PB6) for all pigs, all poultry species for fattening or reared for laying/breeding, laying hens, minor poultry species for laying and ornamental birds (Kemin Europa N.V.)

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the preparation consisting of viable spores of Bacillus velezensis ATCC PTA‐6737 (tradename PB6). PB6 is currently authorised for use as a zootechnical additive (functional group: gut flora stabilisers) for all poultry
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Katerina Theodoridou, Montserrat Anguita, Matteo L. Innocenti, Jaume Galobart, Rosella Brozzi   +19 more
wiley   +1 more source

Effect of monensin on milk production efficiency and milk composition in lactating dairy cows fed modern diets

Journal of Dairy Science
: Since the US Food and Drug Administration's approval of monensin in 2004, significant nutritional advances have been made to increase feed efficiency and milk fat production. Recent evidence suggests monensin's adverse effect on milk fat percentage may
E.A. Horst, S.K. Kvidera, S. Hagerty, P.D. French, D.B. Carlson, K. Dhuyvetter, A.W. Holloway   +6 more
doaj   +1 more source