Results 151 to 160 of about 45,229 (308)
Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis
British Journal of Clinical Pharmacology, EarlyView.Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić +4 more
wiley +1 more source
REGIONAL COOPERATION AND INTEGRATION IN SUB-SAHARAN AFRICA [PDF]
Africa has a long tradition of regional cooperation, its trade and monetary integration schemes being the oldest in the developing world. This paper analyses the state of regional integration with respect to trade and financial relations in selected ...
Martina Metzger
core
How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU
British Journal of Clinical Pharmacology, EarlyView.The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley +1 more source
Neural Representations and Functional Connections Underlie Subjective Positive Affect. [PDF]
J NeurosciSavalia T +4 more
europepmc +1 more source
The Path towards Economic and Monetary Integration: The Portuguese Experience [PDF]
The Portuguese economy initiated its path towards economic and monetary integration in 1960 by taking part in the group of countries that founded the European Free Trade Association.
Joao Amador
core
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
A novel hybrid deep learning framework for customer churn prediction using RFM and embedding clustering. [PDF]
Sci RepIbrahim S +3 more
europepmc +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
A methodological comparative analysis of monetary policy and trade openness on economic growth in West Africa: Does language play a role? [PDF]
PLoS OneBoateng SA, Enimil B, Takyi-Danquah E.
europepmc +1 more source