Results 131 to 140 of about 382,652 (266)

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp   +7 more
wiley   +1 more source

Thiophene Containing Polycyclic Aromatic Hydrocarbon Monkey Saddles

open access: yesAsian Journal of Organic Chemistry, Accepted Article.
Negatively curved chiral polycyclic aromatic hydrocarbons (PAHs) gained a lot of interest in research over the past years. By replacing phenyl against thiophene units in a monkey saddle shaped PAH, it was possible to further tune the photophysical and electrochemical properties as well as influence the racemization barrier of these three‐dimensional ...
Tobias Kirschbaum   +6 more
wiley   +1 more source

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