Results 61 to 70 of about 99,269 (234)
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao +12 more
wiley +1 more source
Operant conditioning in the Mongolian gerbil [PDF]
Mongolian gerbils learned to press a response button to obtain food reward. Responding under three reinforcement schedules was then observed: first, reinforcement occurred after every response; responding was then reinforced on a 15-sec variable-interval schedule; finally, responding was reinforced on a 1-min variable interval.
Nancy Campbell +2 more
openaire +1 more source
ABSTRACT Neural bases of aggression have been analysed mainly in rodent males, finding that the medial preoptic area (mPOA), bed nucleus of the stria terminalis (BNST) ventromedial hypothalamus (VMH), anterior hypothalamus (AHN), and medial amygdala (MeA) integrate the core aggression circuit.
Héctor Reyes‐Arenas +6 more
wiley +1 more source
Density of dopaminergic fibres in the prefrontal cortex of gerbils is sensitive to aging
Mesencephalic dopamine (DA) projections are essential for cognitive and behavioral functions and believed to play a critical role during development and aging.
Teuchert-Noodt Gertraud +1 more
doaj +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
BackgroundOnchocerciasis currently afflicts an estimated 15 million people and is the second leading infectious cause of blindness world-wide. The development of a macrofilaricide to cure the disease has been hindered by the lack of appropriate small ...
Fidelis Cho-Ngwa +8 more
doaj +1 more source
BackgroundOnchocerciasis (river blindness) caused by the filarial worm Onchocerca volvulus is a neglected tropical disease that affects the skin and eyes of humans.
Rene Bilingwe Ayiseh +6 more
doaj +1 more source
Nutrient‐focused dietary strategies can enhance BAT function and activity, thereby contributing to the modulation of metabolic disorders and the optimization of metabolic health. ABSTRACT Brown adipose tissue (BAT) and beige adipose tissue (beige fat) function as thermogenic organs, significantly influencing human metabolism through various mechanisms.
Yuqun Wang +5 more
wiley +1 more source
Salicylate-Induced Changes in Hearing Thresholds in Mongolian Gerbils Are Correlated With Tinnitus Frequency but Not With Tinnitus Strength [PDF]
Veralice Lanaia +2 more
openalex +1 more source
Micro‐CT Analysis of Rodent Temporal Bones: Identifying Optimal Species for Otological Research
ABSTRACT Objectives Rodents are used in most otological research studies and the choice of the most appropriate animal model may be crucial in studies of ear diseases and in the development of effective treatments. Here, we used micro‐CT to compare temporal bone anatomy between four rodent model animals (guinea pigs, gerbils, rats, and mice) and humans,
Hannah Daoudi +8 more
wiley +1 more source

