Results 61 to 70 of about 347,059 (235)

Scalable Fabrication of MOF Glass Membranes for Gas Separation via Stepwise Phase Transition

Advanced Science, EarlyView.
Metal‐organic framework (MOF) glass membranes, with their excellent processability and permanent pore structure, have great potential for gas separation applications. However, during large‐scale fabrication, defects and obvious cracks are prone to occur due to the limitations of powder processing.
Mao Ye, Yi Yang, Zibo Yang, Yuxiu Sun, De Ao, Fan Zhou, Ying Chen, Chunhui Luo, Ziyao Wang, Wenjia Sun, Yunling Jia, Wengang Huang, Jingwei Hou, Zhi Wang, Zhihua Qiao   +14 more
wiley   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

Advanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu, Jiachen Wang, Chunmeng Ding, Changfa Xia, Yunyong Liu, Yuanjie Zheng, Sheng Chang, Shaokai Zhang, Yutong He, Ruifang Sun, Yunfeng Xi, Yan Liu, Kun Qian, Wanqing Chen   +13 more
wiley   +1 more source

Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

Advanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu, Yufei Sun, Xinlei Wu, Haixia Chen, Shaocong Mo, Zichong Li, Yiwei Gong, Xiaoqian Shan, Yuanqi Li, Yaru Guan, Junqi Zhu, Han Yan, Min Du, Feng Wei, Peixin Ou, Ziyi Wang, Chenting Zhang, Lei Xu, Wenju Lu, Jian Wang, Kai Yang   +20 more
wiley   +1 more source

FREQUENCY OF PIGMENTED BIRTHMARKS IN NEWBORNS OF VARIOUS ETHNIC GROUPS OF PAKISTAN

Pakistan Armed Forces Medical Journal, 2011
Objective: To determine the frequency of various types of pigmented birthmarks in neonates of different ethnic background born at PNS Shifa, with in 48 hours of birth.
Uzam Bashir, Rehan ud din, Najia Ahmed
doaj   +2 more sources

Helicobacter pylori cag-Pathogenicity island-dependent early immunological response triggers later precancerous gastric changes in Mongolian gerbils [PDF]

, 2009
Infection with Helicobacter pylori, carrying a functional cag type IV secretion system (cag-T4SS) to inject the Cytotoxin associated antigen (CagA) into gastric cells, is associated with an increased risk for severe gastric diseases in humans.
Haas, Rainer, Rainer Haas, Wiedemann, Tobias, Loell, Eva, Tobias Wiedemann, Eva Loell, Susanna Mueller, Stolte, Manfred, Stoeckelhuber, Mechthild, Rieder, Gabriele, Manfred Stolte, Gabriele Rieder, Mueller, Susanna, Mechthild Stoeckelhuber   +13 more
core   +2 more sources

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

Advanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu, Xinyuan Zhang, Xinyi Chen, Jiaxin Shi, Meng Xu, Fuhao Wang, Jinling Lv, Jiaman Sun, Weiyi Niu, Zihan Liu, Li Li, Fufeng Liu, Xiangming Wang   +12 more
wiley   +1 more source

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

Advanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao, Zhiwei Cheng, Kai Tian, Mengxiong Sun, Zhuoying Wang, Ming Jiao, Jens Luebeck, Kaiyuan Zhu, Xiao Zhang, Dongqing Zuo, Hongsheng Wang, Chongren Wang, Jiakang Shen, Xiaojun Ma, Gangyang Wang, Zongyi Wang, Jing Han, Kaiyuan Liu, Haoran Mu, Weiqi Ma, Yongyong Ren, Shibing Guo, Huangxin Tu, Lingfeng Yu, Yining Tao, Yu Lv, Hui Lu, Owen S. Chapman, Rishaan Kenkre, Lukas Chavez, Zhengdong Cai, Yuqin Yang, Wei Sun, Yafei Jiang, Yingqi Hua   +34 more
wiley   +1 more source

Praseodymium‐Modulated NiFe Layered Double Hydroxide with Enhanced Oxygen Evolution Activity and Extended Durability

Advanced Science, EarlyView.
Pr doping of NiFe‐LDH simultaneously tunes Ni 3d electronics and mesopore architecture. The optimized Ni2Fe0.88Pr0.12‐LDH switches the OER rate‐determining step, delivers 407 mV at 500 mA cm−2, and sustains 2190 h in half‐cell tests. An AEM electrolyzer with this anode operates over 1000 h at industrial current density, offering a durable rare‐earth ...
Yuanming Gao, Xuezhen Wu, Lin Zhang, Haoxiang Zhang, Xueying Feng, Yu Bai, Wei Song, Yong Zheng, Jiong Liu, Jieyu Chen, Dong Yang, Wen Ma, Shengzhong (Frank) Liu   +12 more
wiley   +1 more source

Hydrogen Production from Ammonia Electrochemical Cracking

Advanced Science, EarlyView.
NH3 electrochemical cracking (e‐cracking) is a complementary technique to centralized thermal cracking for releasing H2 from NH3. In this article, we review recent advances in catalyst development for these cracking techniques and conduct a techno‐economic analysis (TEA) to evaluate the economic feasibility of e‐cracking.
Yike Ye, Yi Shun Lim, Qian Wu, Kamal Elouarzaki, Zhichuan J. Xu   +4 more
wiley   +1 more source

THE INCIDENCE OF BIRTHMARKS IN IRANIAN NEONATES [PDF]

Acta Medica Iranica, 2007
A number of innocent rashes occurs in neonates. They are usually transient and self limited and thus require no therapy but early recognition is important to distinguish these lesions from more serious disorders.
H. Shajari, A. Shajari, N. Sajadian M. Habiby   +2 more
doaj   +2 more sources