Results 101 to 110 of about 2,600,115 (310)

Peaks Over Threshold Method for Structural Health Monitoring Detector Design [PDF]

, 2015
Structural Health Monitoring (SHM) system offers new approaches to interrogate the integrity of structures. The most critical step of such systems is the damage detection step since it is the first and because performances of the following steps (damage ...
NAZIH MECHBAL, MECHBAL, Nazih, HMAD, Ouadie, MARC REBILLAT, RÉBILLAT, Marc, OUADIE HMAD   +5 more
core   +1 more source

A Physiologic Approach to Hemodynamic Monitoring and Optimizing Oxygen Delivery in Shock Resuscitation.

, 2020
The approach to shock resuscitation focuses on all components of oxygen delivery, including preload, afterload, contractility, hemoglobin, and oxygen saturation.
Russell, Amy, Jaehne, Anja K, Giri, Paresh C, Nguyen, H Bryant, Rivers, Emanuel P   +4 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

NILMTK: An open source toolkit for non-intrusive load monitoring

Non-intrusive load monitoring, or energy disaggregation, aims to separate household energy consumption data collected from a single point of measurement into appliance-level consumption data.
Parson, Oliver, Batra, Nipun, Knottenbelt, William, Kelly, Jack, Rogers, Alex, Srivastava, Mani, Singh, Amarjeet, Dutta, Haimonti   +7 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Pre-Intubation Resuscitation (Physiologic Optimization)

Pre-Intubation Resuscitation (Physiologic Optimization) reviews indications, preparation, equipment selection, procedural sequence, placement confirmation, device security, complication recognition, and rescue options for advanced airway care in remote ...
Casey C. Sears
core   +1 more source

A comprehensive cross-sectional study of bedside monitor alarm characteristics and alarm load across hospital units

Scientific Reports
Bedside physiologic monitor alarms negatively contribute to clinician cognitive burden and patient wellbeing in hospital intermediate (IMCU) and intensive (ICU) care units. This was a cross-sectional study to characterize the types, sources, annunciation
Karina Kraevsky, Sajida Aqtash, Fanurs Chi-En Teh, Michael R. Pinsky, Gilles Clermont, Marilyn Hravnak, Salah S. Al-Zaiti   +6 more
doaj   +1 more source