Results 41 to 50 of about 73,907 (244)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Detecting early physiologic changes through cardiac implantable electronic device data among patients with COVID-19

Cardiovascular Digital Health Journal, 2022
Background: Cardiac implantable electronic devices (CIEDs) may enable early identification of COVID-19 to facilitate timelier intervention. Objective: To characterize early physiologic changes associated with the onset of acute COVID-19 infection, as ...
Meghan Reading Turchioe, PhD, MPH, RN, Rezwan Ahmed, PhD, Ruth Masterson Creber, PhD, MSc, RN, Kelly Axsom, MD, Evelyn Horn, MD, Gabriel Sayer, MD, Nir Uriel, MD, Kenneth Stein, MD, FHRS, David Slotwiner, MD, FHRS   +8 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

3-Dimensional Physiologic Postural Range of the Mandible: A Computerized-Assisted Technique—A Case Study

Case Reports in Medicine, 2013
Previous studies demonstrated that while the mandible assumes its resting position in space, antagonistic muscles should assume minimal muscle activity within a spatial range.
Todd Shewman
doaj   +1 more source

Predicting patient decompensation from continuous physiologic monitoring in the emergency department

npj Digital Medicine, 2023
Anticipation of clinical decompensation is essential for effective emergency and critical care. In this study, we develop a multimodal machine learning approach to predict the onset of new vital sign abnormalities (tachycardia, hypotension, hypoxia) in ...
Sameer Sundrani, Julie Chen, Boyang Tom Jin, Zahra Shakeri Hossein Abad, Pranav Rajpurkar, David Kim   +5 more
doaj   +1 more source

Hemodynamic monitoring and outcome—A physiological appraisal

Acta Anaesthesiologica Taiwanica, 2011
Hemodynamic monitoring provides us with refined details about the cardiovascular system. In spite of increased availability of the monitoring process and monitoring equipment, hemodynamic monitoring has not significantly improved survival outcome. Care providers should be cognizant of the role of the cardiovascular system and its importance in oxygen ...
Chan, Y.K., Khan, Z.H
openaire   +3 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Effectiveness, implementation, and monitoring variables of intermittent hypoxic bicycle training in patients recovered from COVID-19: The AEROBICOVID study

Frontiers in Physiology, 2022
Hypoxic exposure is safely associated with exercise for many pathological conditions, providing additional effects on health outcomes. COVID-19 is a new disease, so the physiological repercussions caused by exercise in affected patients and the safety of
Gabriel Peinado Costa, Alba Camacho-Cardenosa, Javier Brazo-Sayavera, Javier Brazo-Sayavera, Marcela Coffacci De Lima Viliod, Marta Camacho-Cardenosa, Yan Figueiredo Foresti, Carlos Dellavechia de Carvalho, Eugenio Merellano-Navarro, Marcelo Papoti, Marcelo Papoti, Átila Alexandre Trapé   +11 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Multimodal monitoring system in traumatic brain injury

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Traumatic brain injury (TBI) poses great threats to human health. Due to complicated progresses of primary and secondary injuries, patients' conditions are unstable and thus influence the prognosis.
Hua FENG, Wen-yan LI, Liang TAN, Tu-nan CHEN   +3 more
doaj