Results 61 to 70 of about 2,600,115 (310)

Physiologic monitoring and anesthesia considerations in acute ischemic stroke

, 2004
Acute ischemic stroke is considered a neurologic emergency. The perioperative anesthesia management of acute ischemic stroke is challenging owing to the dynamic pathophysiology of the disease itself and the patients\u27 comorbid factors and conditions ...
Hashimoto, Tomoki, Litt, Lawrence, Lee, Chanhung Z, Young, William L   +3 more
core   +1 more source

Multimodal monitoring system in traumatic brain injury

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Traumatic brain injury (TBI) poses great threats to human health. Due to complicated progresses of primary and secondary injuries, patients' conditions are unstable and thus influence the prognosis.
Hua FENG, Wen-yan LI, Liang TAN, Tu-nan CHEN   +3 more
doaj  

3-Dimensional Physiologic Postural Range of the Mandible: A Computerized-Assisted Technique—A Case Study

Case Reports in Medicine, 2013
Previous studies demonstrated that while the mandible assumes its resting position in space, antagonistic muscles should assume minimal muscle activity within a spatial range.
Todd Shewman
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Toward optimal display of physiologic status in critical care: I. Recreating bedside displays from archived physiologic data

, 2010
BACKGROUND: Physiologic data display is essential to decision making in critical care. Current displays echo first-generation hemodynamic monitors dating to the 1970s and have not kept pace with new insights into physiology or the needs of clinicians who
Vannucci, Andrea, Burykin, Anton, Krejci, Vladimir, Kangrga, Ivan, Peck, Tyler, Buchman, Timothy G, Andrea Vannucci, Ivan Kangrga, Anton Burykin, Timothy G. Buchman, Tyler Peck, Vladimir Krejci   +11 more
core   +1 more source

Predicting patient decompensation from continuous physiologic monitoring in the emergency department

npj Digital Medicine, 2023
Anticipation of clinical decompensation is essential for effective emergency and critical care. In this study, we develop a multimodal machine learning approach to predict the onset of new vital sign abnormalities (tachycardia, hypotension, hypoxia) in ...
Sameer Sundrani, Julie Chen, Boyang Tom Jin, Zahra Shakeri Hossein Abad, Pranav Rajpurkar, David Kim   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Office of Desegregation Monitoring records [DIGITAL CONTENT]

, 1950
This collection contains records from the Office of Desegregation Monitoring, including legal documents, correspondence, news clippings, maps, school profiles, monitoring and various other reports concerning school district compliances, operations, and ...
Office of Desegregation Monitoring (Little Rock, Ark.)
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source