Results 81 to 90 of about 5,140,819 (312)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

"Interactive technology assessment" and beyond: the field trial of genetically modified grapevines at INRA-Colmar. [PDF]

open access: yesPLoS Biology, 2010
Local Monitoring Committee   +3 more
doaj   +1 more source

Distribution characteristics and origin analysis of iron and manganese in groundwater in Beijing Plain Area

open access: yesShuiwen dizhi gongcheng dizhi
Groundwater is an important part of Beijing’s water supply, excessive ferric and manganese in groundwater will limit the development and utilization of water resources.
Jiji CHEN   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Suggestions for the Construction of the Regional Monitoring System of the Yellow Sea Large Marine Ecosystem

open access: yesHaiyang Kaifa yu guanli, 2022
In order to promote the ecological environment protection and ecological disaster control of Yellow Sea, this paper analyzed the background of ecological environment and problems, and put forward suggestions for the construction of regional monitoring ...
Xiaocheng WANG   +10 more
doaj  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Responses of Groundwater Bacterial Communities to Extreme Rainfall in the Western North China Plain Based on 16S rRNA Sequencing

open access: yesMicroorganisms
Extreme rainfall events significantly affect groundwater systems by altering hydrogeological conditions and accelerating the migration of pollutants, exacerbating the ecological vulnerability of over-exploited areas.
Yuan Gao   +11 more
doaj   +1 more source

Oregon Beach Monitoring Program: frequently asked questions

open access: yes, 2005
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on May 31, 2011)"DHS 8654 ...

core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

U.S. Census Monitoring Board Congressional Members: Bi-Annual Report

open access: yes, 2001
Congress established the Census Monitoring Board to observe and monitor all aspects of the preparation and implementation of the 2000 decennial census.
U.S. Census Monitoring Board. Congressional Members.
core  

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