Results 111 to 120 of about 5,150,901 (309)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Monitoring distributed object and component communication [PDF]
, 2004 This thesis presents our work in the area of monitoring distributed software applications (DSAs). We produce three main results: (1) a design approach for building monitoring systems, (2) a design of a system for MOnitoring Distributed Object and ...
Diakov, Nikolay Kirilov
core +3 more sources
Open-Source ANSS Quake Monitoring System Software [PDF]
, 2020 ANSS stands for the Advanced National Seismic System of the U.S.A., and ANSS Quake Monitoring System (AQMS) is the earthquake management system (EMS) that most of its member regional seismic networks (RSNs) use. AQMS is based on Earthworm, but instead of
Bhadha, Rayomand +4 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Software control for large scale on-board checkout: A concept [PDF]
, 1972 Two level system checkout in which first level satisfies continuous monitoring requirements and second level provides fault isolation to satisfy maintenance requirements, provides self-checking capability for monitoring system and enables recovery from ...
Grounds, H. K., Norton, D. H., Jr.
core +1 more source
Application of an Ultrasonic Sensor to Monitor Soil Erosion and Deposition [PDF]
, 2020 While erosion and deposition are naturally occurring processes, these processes can be accelerated by human influences. The acceleration of erosion causes damage to human assets and costs billions of dollars to mitigate.
Johnson, Jessica E
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Intelligent defect classification system based on deep learning
Advances in Mechanical Engineering, 2018 A fast and intelligent defect classification system for distinguishing defect features is developed in this study. Defect images obtained from an automated optical inspection instrument are first trained utilizing a deep learning approach based on the ...
Ruifang Ye +3 more
doaj +1 more source