Results 121 to 130 of about 5,150,901 (309)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

ATLAS Pixel Radiation Monitoring with HVPP4 System [PDF]

open access: yes, 2009
In this talk we present the basis for the protocol for radiation monitoring of the ATLAS Pixel Sensors. The monitoring is based on a current measurement system, HVPP4. The status on the ATLAS HVPP4 system development is also presented.Comment: Talk given
Gorelov, Igor   +3 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Zebrafish as a rapid model system for early cardiotoxicity assessment of drugs

open access: yesJournal of Holistic Integrative Pharmacy
Objective: There are some problems in the evaluation of drug cardiotoxicity in zebrafish, such as unsystematic indicators and weak sensitivity.
Zonghao Lin   +8 more
doaj   +1 more source

Wireless sensor network for cattle monitoring system [PDF]

open access: yes, 2009
This paper describes a cost effective Wireless Sensor Network (WSN) technology for monitoring the health of dairy cows. By monitoring and understanding the cow individual and herd behaviour, farmers can potentially identify the onset of illness, lameness
Andonovic, I.   +4 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

PDA-based system for monitoring electromagnetic signals [PDF]

open access: yes, 2006
The development of a mobile system for receiving, storing, and displaying electromagnetic-signals (EM) at specific frequencies using mobile devices and wireless networks, is of extreme interest, especially when the final means of display is a PDA, a very
Banitsas, K   +4 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Solar proton monitoring system [PDF]

open access: yes
Solar proton monitoring system in North ...
Adams, G. W., Megill, L. R.
core   +1 more source

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