Results 111 to 120 of about 10,314 (285)
RF/SS system for wireless local loop [PDF]
In this communication we deal with the use of direct sequence spread spectrum tecllniques for radio transmission in the local loop. We present a direct sequence spread-spectrum system that is being developed to transmit signals from ISDN-U ...
Burgos, Mateo +5 more
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A difficult intensive care unit monitorization case: a suicidal attempt at 13 years of age by hanging [PDF]
Suicide among young population is a global challenge increasing over time. Family problems, drug addiction, increased risk of childhood depression may lead to suicidal attempts by hanging with a rope, which is a rarely selected method at younger ages ...
isa yildiz +5 more
doaj
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Dynamic monitorization of structures with optical sensors [PDF]
Fiber optical sensors, namely Fiber Bragg gratings, are one the most promising technologies in several sensing systems. This sensing technology could be useful and cost effective in most civil engineering infrastructures.
André, P., Antunes, P., Varum, H.
core
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source

