Results 1 to 10 of about 1,048,144 (219)

Overcoming Transmission Barriers: A Dual-Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing. [PDF]

open access: yesAdv Sci (Weinh)
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Zhang M   +7 more
europepmc   +2 more sources

Identification of Repurposed Drugs Against Monkeypox Virus Through Comprehensive Virtual Screening. [PDF]

open access: yesBiotechnol J
Graphical Abstract and Lay Summary By combining interspecies protein analysis with advanced virtual screening, this study identifies potent repurposed drug candidates—including vindesine and LY2090314—targeting mpox DNA topoisomerase and polymerase. This workflow provides a rapid, practical framework for antiviral discovery against emerging infectious ...
Yu T, Jang WD, Lee SY.
europepmc   +2 more sources

Mechanisms of immune evasion of monkeypox virus

open access: yesFrontiers in Microbiology, 2023
The mpox (disease caused by the monkeypox virus) epidemic in 2022 provides a good opportunity to study the immune response to mpox. Vaccinia virus-infected monocytes could be recognized by monkeypox virus-specific CD4+ and CD8+ T cells, which produce ...
Milad Zandi   +4 more
doaj   +3 more sources

Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

open access: yesLife, 2023
Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects.
Faheem Anwar   +9 more
doaj   +3 more sources

Knowledge and Attitudes of Healthcare Workers Toward the Re-Emergence of Human Monkeypox Virus Infection in Public Health Facilities in the Central Ethiopia Region: An Online Cross-Sectional Study. [PDF]

open access: yesHealth Sci Rep
ABSTRACT Background and Aims Human monkeypox (mpox) is a re‐emerging zoonotic viral disease in Africa. Despite recent reports in Ethiopia, no studies have assessed healthcare workers' (HCWs) knowledge and attitudes in the Central Ethiopia Region. This study aimed to determine HCWs knowledge and attitudes toward the re‐emergence of mpox in public health
Larebo YM   +5 more
europepmc   +2 more sources

Mini review on the monkeypox: a new human threat (2007–2022) [PDF]

open access: yesERU Research Journal, 2022
While the world is still dealing with the coronavirus disease 2019 (COVID-19) pandemic, the emergence of a new outbreak caused by the monkeypox virus has public health officials concerned about whether it will pose a new threat.
Veronica Nabil, Mohamed Sayed
doaj   +1 more source

MONKEYPOX: FACTS ABOUT THE DISEASE [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2022
Monkeypox is a zoonotic disease caused by the monkeypox virus of the genus Orthopoxvirus genus and Poxiviridae family. Many animal species, including rodents and monkeys, can transmit the virus. However, the natural reservoir is unknown yet.
Kanaan Al-Tameemi   +2 more
doaj   +1 more source

Monkeypox Pathogenesis, Transmission, Preventive Measures and Treatment Modalities [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Monkeypox is a disease transmitted through animals but can also spread from human to human. The causative agent is monkeypox virus which is a ds-DNA virus. Monkeypox virus belongs to the orthopox genus of the poxviridae family.
Vaishnavi Uttam Goradwar, Anil Agrawal
doaj   +1 more source

Evaluation of Five Buffers for Inactivation of Monkeypox Virus and Feasibility of Virus Detection Using the Panther Fusion® Open Access System

open access: yesViruses, 2022
Rapid diagnosis is key to containing viral outbreaks. However, for the current monkeypox outbreak the major deterrent to rapid testing is the requirement for higher biocontainment of potentially infectious monkeypox virus specimens.
Robert J. Fischer   +5 more
doaj   +1 more source

Detection of Monkeypox Virus according to The Collection Site of Samples from Confirmed Cases: A Systematic Review

open access: yesTropical Medicine and Infectious Disease, 2022
Due to the rapid evolution of the monkeypox virus, the means by which the monkeypox virus is spread is subject to change. Therefore, the present study aims to analyze the detection of the monkeypox virus according to the collection site of samples from ...
Darwin A. León-Figueroa   +7 more
doaj   +1 more source

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