Results 1 to 10 of about 770 (66)
An Update of Orthopoxvirus Molecular Evolution
Viruses, 2022 Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete ...
Igor V Babkin
exaly +3 more sources
An Increasing Danger of Zoonotic Orthopoxvirus Infections [PDF]
PLoS Pathogens, 2013 On May 8, 1980, the World Health Assembly at its 33(rd) session solemnly declared that the world and all its peoples had won freedom from smallpox and recommended ceasing the vaccination of the population against smallpox. Currently, a larger part of the
Sergey Shchelkunov
exaly +2 more sources
Emerging Microbes and Infections, 2023 The worldwide outbreak of the monkeypox virus (MPXV) has become a “Public Health Emergency of International Concern” (PHEIC). Severe monkeypox virus infection can be fatal, however, effective therapeutic methods are yet to be developed.
Jiayin Chen, Mengjun Li
exaly +3 more sources
Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections
Viruses, 2010 Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N Isaacs, Yuhong Xiao
exaly +3 more sources
Orthopoxvirus Seroprevalence and Infection Susceptibility in France, Bolivia, Laos, and Mali
Emerging Infectious Diseases, 2022 To determine a demographic overview of orthopoxvirus seroprevalence, we tested blood samples collected during 2003–2019 from France (n = 4,876), Bolivia (n = 601), Laos (n = 657), and Mali (n = 255) for neutralizing antibodies against vaccinia virus. In
Léa Luciani +11 more
doaj +1 more source
The French Armed Forces Virology Unit: A Chronological Record of Ongoing Research on Orthopoxvirus
Viruses, 2017 Since the official declaration of smallpox eradication in 1980, the general population vaccination has ceased worldwide. Therefore, people under 40 year old are generally not vaccinated against smallpox and have no cross protection against orthopoxvirus ...
Déborah Delaune +4 more
doaj +1 more source
Viruses, 2010 The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller +4 more
doaj +1 more source
Rapid and high-throughput pan-Orthopoxvirus detection and identification using PCR and mass spectrometry. [PDF]
PLoS ONE, 2009 The genus Orthopoxvirus contains several species of related viruses, including the causative agent of smallpox (Variola virus). In addition to smallpox, several other members of the genus are capable of causing human infection, including monkeypox ...
Mark W Eshoo +16 more
doaj +1 more source
Priming stroma with a vitamin D analog to optimize viroimmunotherapy for pancreatic cancer
Molecular Therapy: Oncolytics, 2022 Pancreatic cancer resistance to immunotherapies is partly due to deficits in tumor-infiltrating immune cells and stromal density. Combination therapies that modify stroma and recruit immune cells are needed.
Sang-In Kim +13 more
doaj +1 more source
Vaccinia Virus Infection in Monkeys, Brazilian Amazon
Emerging Infectious Diseases, 2010 To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples.
Jônatas S. Abrahão +13 more
doaj +1 more source