An Update of Orthopoxvirus Molecular Evolution [PDF]
Viruses, 2022 Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete ...
Igor V Babkin
exaly +5 more sources
Zoonotic Orthopoxvirus Infection [PDF]
Case Reports in DermatologyIntroduction: Cowpox virus (CPXV) is a rare zoonotic orthopoxvirus infection, most commonly transmitted to humans via infected domestic cats.
Bernadett Kurz +5 more
doaj +3 more sources
Pox-AbDab: the orthopoxvirus antibody database [PDF]
Frontiers in ImmunologyIn August 2024, the World Health Organization declared the mpox orthopoxvirus to be a Public Health Emergency of International Concern for the second time in three years, emphasising the need for continued studies into its microbiology and potential ...
Henriette L. Capel +4 more
doaj +5 more sources
A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]
Health Sci RepABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB +6 more
europepmc +2 more sources
Emerging Microbes and Infections, 2023 The worldwide outbreak of the monkeypox virus (MPXV) has become a “Public Health Emergency of International Concern” (PHEIC). Severe monkeypox virus infection can be fatal, however, effective therapeutic methods are yet to be developed.
Jiayin Chen
exaly +3 more sources
ENDEMIC ORTHOPOXVIRUS CIRCULATING IN PROCYONIDS IN MEXICO [PDF]
Journal of Wildlife Diseases, 2016 Limited serosurveillance studies suggested that orthopoxviruses (OPXV) are widespread in the US (e.g., Raccoonpox virus, Skunkpox virus, Volepox virus) and Brazil (Vaccinia virus); however, their animal reservoir(s) remain unconfirmed. Mexican mammal diversity includes several species related to those in which evidence for OPXV infections has been ...
Claudia Villanueva +2 more
exaly +3 more sources
Trends of Pathogenicity and Potential Risk Evaluation of Central African Mpox Variant to Cause Global Public Health Emergency: A Cross-Sectional Analysis. [PDF]
Health Sci RepABSTRACT Background With the re‐emergence of monkeypox (Mpox), it is vital for communities to assess and effectively respond to emerging outbreaks. This paper aims to review the potential of clade I Mpox to result in a widespread outbreak by assessing genetically enhanced virulence, transmission, and clinical manifestations.
Rahman MA +5 more
europepmc +2 more sources
Vaccinia and Monkeypox Virus-Neutralizing Antibodies in People Living with HIV: A Serological Study in a Orthopoxvirus-Endemic, Low-Income Region in Brazil [PDF]
PathogensCo-infections of Orthopoxviruses (OPVs), such as vaccinia virus (VACV) and monkeypox virus (MPXV), and the human immunodeficiency virus (HIV) can be associated with severe outcomes.
Thyago José Silva +10 more
doaj +2 more sources
Skin lesions caused by Orthopoxvirus, cowpox - case report from Poland
Journal of Education, Health and Sport, 2021 Background:Despite the elimination of smallpox, other orthopoxviruses, including cowpox virus, still infect humans. Wild rodents are its natural reservoir.
Konrad Kania +4 more
doaj +1 more source
Priming stroma with a vitamin D analog to optimize viroimmunotherapy for pancreatic cancer
Molecular Therapy: Oncolytics, 2022 Pancreatic cancer resistance to immunotherapies is partly due to deficits in tumor-infiltrating immune cells and stromal density. Combination therapies that modify stroma and recruit immune cells are needed.
Sang-In Kim +13 more
doaj +1 more source