Results 41 to 50 of about 1,689,796 (314)

Tecovirimat as a Potential Bioavailable inhibitor against MPXVgp158 Established through Molecular Dynamic Simulations and Docking Studies

Journal of Pure and Applied Microbiology, 2022
Monkeypox is a zoonotic viral infection caused by monkeypox virus which belongs to the Poxviridae family of genus Orthopoxvirus. Usually, the virus transmission happens when the individual comes in contact with the infected person through body fluids ...
Varruchi Sharma, Anil Panwar, Vivek Kumar Garg, Hardeep Singh Tuli, Sonal Datta, Anil K Sharma, Abhijit Dey, Deepak Chandran, Kuldeep Dhama   +8 more
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The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG, de Quadros, CA, Dowdle, WR, Foege, WH, Henderson, DA, John, TJ, Levine, MM   +6 more
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Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model

Proceedings of the National Academy of Sciences of the United States of America, 2023
Significance Three clades of mpox (monkeypox) virus are recognized: Clade I is present in the Congo Basin, causes up to 10% human mortality, and is transmitted by rodents with little human-to-human spread; clade IIa exists in West Africa, has a low ...
Jeffrey L. Americo, P. Earl, B. Moss
semanticscholar   +1 more source

The first strain of monkeypox isolated in the Chinese Mainland and preserved at the National Pathogen Resource Center of China

Infectious Medicine, 2022
On September 16, 2022, the first imported monkeypox case was reported in the Chinese Mainland. Laboratory tests including nucleic acid detection were carried out in Chongqing Nan'an Centre for Disease Control and Prevention and Chongqing Center for ...
Qiang Wei, Baoying Huang, Wei Huang, Jingdong Song, Li Mei, Li Zhao, Jing Yin, Juan Zhang, Wenling Wang, Fei Ye, Caiyun Li, Liling Bai, Yanhai Wang, Yao Deng, Bo Liu, Mengnan Jiang, Guizhen Wu, Jun Han, Hua Zhao, Hua Ling, Wenjie Tan, Jianjun Liu   +21 more
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Macaque models of human infectious disease. [PDF]

, 2008
Macaques have served as models for more than 70 human infectious diseases of diverse etiologies, including a multitude of agents-bacteria, viruses, fungi, parasites, prions.
Abe, Adams, Ahmed, Ajariyakhajorn, Albrecht, Allen, Apetrei, Apetrei, Arroyo, Bai, Bannantine, Barker, Barnett, Barouch, Baskerville, Baskin, Baze, Bennett, Blanchard, Blaney, Bons, Boonjakuakul, Breitschwerdt, Brooks, Brown, Bruce, Campos, Capone, Capone, Carbone, Carlson, Carlson, CARVALHO, Chan, Chattopadhyay, Chen, Chen, Chenine, Choi, Chomel, Choo, Chopra, Christe, Coalson, Coban, Cohen, Cohen, Contreras, Courgnaud, Custer, Cypess, Daddario-DiCaprio, Daddario-Dicaprio, Dalgard, Daniel, de Swart, Dezzutti, Di Giulio, Dittmer, Doi, Donnelly, Dubois, Dubois, Dutta, Earl, Edghill-Smith, Edghill-Smith, Ekanayake, Engel, Escalante, Espana, Farber, Feichtinger, Fisher-Hoch, Fisher-Hoch, Fitzgeorge, Fogg, Foley, Foucault, Fritz, Frolova, Gajdusek, Gallinella, Gao, Gardner, Gardner, Gardner, Gaynor, Geisbert, Geisbert, Geisbert, Geisbert, Gheit, Gibbs, Giddens, Goldstein, Gonder, Good, Gormus, Gormus, Goverdhan, Graczyk, Graff, Gray, Green, Guirakhoo, Haagmans, Haase, Habis, Hambleton, Hansen, Hawley, Heise, Heraud, Herzog, Hessell, Hicks, Higashi, Hirano, Hirsch, Hooper, Hotez, Hubbert, Hull, Hunsmann, Hutin, Ilyinskii, Inoue, Ivanoff, Jahrling, Ji, Johnson, Johnson, Jones-Engel, Jones-Engel, Kao, Kawai, Kawai, Kennedy, Kenyon, Kestler, Kinsey, Kishimoto, Klingstrom, Klumpp, Kobasa, Kobune, Kodama, Kornegay, Kuiken, Kuiken, Kunz, Kutok, Kwang, Lackner, Lake-Bakaar, Lasm  zas, Le Bras, Leong, Leroy, Letvin, Letvin, Letvin, Levine, Li, Li, Lichtenwalner, Lindsley, Line, Ling, Linial, Lockridge, Lodmell, Lowenstine, Lukashevich, Lukashevich, Lusso, Maddison, Mankowski, Mansfield, Mansfield, Marra, Marthas, Marthas, Marx, Mason, Masters, Matz-Rensing, Maul, McArthur-Vaughan, McMichael, McNeely, McShane, Meisenhelder, Mense, Miller, Miyoshi, Moghaddam, Monath, Mon  , Mooser, Morris, Morton, Mulder, Murphey-Corb, Murphy, Murphy, Myint, Nagle, NI, North, Novembre, O'Rourke, O'Sullivan, O'Sullivan, Olson, Ostrow, Ostrow, Oswald, Pachner, Pachner, Pachner, Pahar, Palmer, Palmer, Patton, Patton, Paul, Peiris, Percy, Perelygina, Permar, Persson, Peters, Peters, Petschow, Philipp, Philipp, Phipps, Pialoux, Pletnev, Polack, Pung, Puri, Raengsakulrach, Raether, Ratterree, Reed, Reimann, Reindel, Renne, Rhesus Macaque Genome Sequencing and Analysis Cons, Rimmelzwaan, Rimmelzwaan, Rivailler, Rockx, Rodas, Rue, Ruff, Russell, Saadat, Sale, Samuel, Sato, Schou, Schou, Schricker, Schultz, Sequar, Sestak, Shah, Shen, Shevtsova, Shuto, Simoes, Smit-McBride, Smith, Smith, Soike, Solnick, Solnick, Spencer, Stittelaar, Stittelaar, Stittelaar, Stokes, Subekti, Suss, Tanaka, Tanghe, Taylor, Taylor, Tribe, Tulis, Turell, Uberla, van den Hoogen, van Gorder, Van Heuverswyn, Van Rompay, Van Voorhis, Vasconcelos, Vasconcelos, Veazey, Voevodin, Vogel, Walsh, WALSH, Weinmann, Weiss, Wells, Wengelnik, Wenner, Westerman, White, Whitney, Williamson, Williamson, Willy, Wobus, Wolf, Wolfe, Wood, Wright, Wyatt, Xu, Yalcin, Zaucha, Zhou, Zuckerman, Zumpe   +330 more
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In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy [PDF]

, 2020
Rationale: Zika virus (ZIKV) is a pathogenic virus known to cause a wide range of congenital abnormalities, including microcephaly, Guillain-Barre syndrome, meningoencephalitis, and other neurological complications, in humans. This study investigated the
Hu, Q, Ke, X, Li, P, Liu, Y, Luo, D, Miao, Y, Sun, J, Tan, Z, Wang, H, Wang, T, Xu, F, Zhang, Y, Zheng, Z   +12 more
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Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus

Signal Transduction and Targeted Therapy, 2023
Monkeypox has been declared a public health emergency by the World Health Organization. There is an urgent need for efficient and safe vaccines against the monkeypox virus (MPXV) in response to the rapidly spreading monkeypox epidemic.
Ye Sang, Zhen Zhang, F. Liu, Haitao Lu, Changxiao Yu, Hui-Ling Sun, Jinrong Long, Yiming Cao, Jierui Mai, Yiqi Miao, Xin Wang, Jiaxin Fang, Youchun Wang, Weijing Huang, J. Yang, Shengqi Wang   +15 more
semanticscholar   +1 more source

mRNA vaccines encoding fusion proteins of monkeypox virus antigens protect mice from vaccinia virus challenge

Nature Communications, 2023
The recent outbreaks of mpox have raised concerns over the need for effective vaccines. However, the current approved vaccines have either been associated with safety concerns or are in limited supply.
Fujun Hou, Yuntao Zhang, Xiaohu Liu, Y. Murad, Jiang Xu, Zhibin Yu, Xianwu Hua, Yingying Song, Jun Ding, Hongwei Huang, Ronghua Zhao, W. Jia, Xiaoming Yang   +12 more
semanticscholar   +1 more source

Prediction and prevention of the next pandemic zoonosis. [PDF]

, 2012
Most pandemics--eg, HIV/AIDS, severe acute respiratory syndrome, pandemic influenza--originate in animals, are caused by viruses, and are driven to emerge by ecological, behavioural, or socioeconomic changes.
Carroll, Dennis, Daszak, Peter, Karesh, William B, Lipkin, W Ian, Mazet, Jonna AK, Morse, Stephen S, Parrish, Colin R, Woolhouse, Mark, Zambrana-Torrelio, Carlos   +8 more
core   +1 more source

Evaluation of Virulence in Cynomolgus Macaques Using a Virus Preparation Enriched for the Extracellular Form of Monkeypox Virus

Viruses, 2022
The 2022 global human monkeypox outbreak emphasizes the importance of maintaining poxvirus research, including enriching a basic understanding of animal models for developing and advancing therapeutics and vaccines.
Eric M. Mucker, Josh D. Shamblin, Arthur J. Goff, Todd M. Bell, Christopher Reed, Nancy A. Twenhafel, Jennifer Chapman, Marc Mattix, Derron Alves, Robert F. Garry, Lisa E. Hensley   +10 more
doaj   +1 more source