Results 41 to 50 of about 18,811 (267)

Heat inactivation of monkeypox virus

Journal of Biosafety and Biosecurity, 2022
Different kinds of media spiked with monkeypox virus (MPXV) were subjected to heat inactivation at different temperatures for various periods of time. The results showed that MPXV was inactivated in less than 5 min at 70 °C and less than 15 min at 60 °C, with no difference between viruses from the West African and Central African clades.
Batéjat, Christophe, Grassin, Quentin, Feher, Maxence, Hoinard, Damien, Vanhomwegen, Jessica, Manuguerra, Jean-Claude, Leclercq, India   +6 more
openaire   +4 more sources

Proteomic basis of the antibody response to monkeypox virus infection examined in cynomolgus macaques and a comparison to human smallpox vaccination. [PDF]

PLoS ONE, 2010
Monkeypox is a zoonotic viral disease that occurs primarily in Central and West Africa. A recent outbreak in the United States heightened public health concerns for susceptible human populations.
Sarah Keasey, Christine Pugh, Alexander Tikhonov, Gengxin Chen, Barry Schweitzer, Aysegul Nalca, Robert G Ulrich   +6 more
doaj   +1 more source

Monkeypox virus: past and present

World Journal of Pediatrics, 2022
Abstract Background The objective of this paper is to analyze the current status of monkeypox worldwide. In the face of this public health threat, our purpose is to elucidate the clinical characteristics and epidemiology of monkeypox, the developmental progress of monkeypox-related drugs and the vaccines available.
Ya-Mei Dou, Hang Yuan, Hou-Wen Tian
openaire   +2 more sources

Elucidating the role of the complement control protein in monkeypox pathogenicity. [PDF]

PLoS ONE, 2012
Monkeypox virus (MPXV) causes a smallpox-like disease in humans. Clinical and epidemiological studies provide evidence of pathogenicity differences between two geographically distinct monkeypox virus clades: the West African and Congo Basin.
Paul N Hudson, Joshua Self, Sonja Weiss, Zachary Braden, Yuhong Xiao, Natasha M Girgis, Ginny Emerson, Christine Hughes, Scott A Sammons, Stuart N Isaacs, Inger K Damon, Victoria A Olson   +11 more
doaj   +1 more source

The recent re-emergence of human monkeypox: Would it become endemic beyond Africa?

Journal of Infection and Public Health, 2023
Viral outbreaks still become global health challenges, for instance, influenza A viruses, Japanese encephalitis, Ebola virus, Yellow fever, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Mohamad S. Hakim, Suci A. Widyaningsih
doaj   +1 more source

Anticipating the species jump: surveillance for emerging viral threats. [PDF]

, 2012
Zoonotic disease surveillance is typically triggered after animal pathogens have already infected humans. Are there ways to identify high-risk viruses before they emerge in humans? If so, then how and where can identifications be made and by what methods?
Bush, RM, Cobey, S, Flanagan, ML, Glass, GE, Leighton, TJ, Parrish, CR   +5 more
core   +1 more source

Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection

Emerging Infectious Diseases, 2022
Beginning in May 2022, a rising number of monkeypox cases were reported in non–monkeypox-endemic countries in the Northern Hemisphere. We adapted 2 published quantitative PCRs for use as a dual-target monkeypox virus test on widely used automated high ...
Dominik Nörz, Hui Ting Tang, Petra Emmerich, Katja Giersch, Nicole Fischer, Stephan Schmiedel, Marylyn M. Addo, Martin Aepfelbacher, Susanne Pfefferle, Marc Lütgehetmann   +9 more
doaj   +1 more source

Monkeypox virus (MPXV)

World Journal of Advanced Research and Reviews, 2022
Monkeypox (MPXV) is a zoonosis with a double-origin DNA (DNA), caused by monkeypox virus, an orthopox virus and close relative of variola virus (smallpox). It was first reported in central Africa in 1970 and has historically affected some of the poorest and most marginalized communities in the world.
openaire   +1 more source

A Comparative Evaluation of Three Diagnostic Assays for the Detection of Human Monkeypox

Viruses
Accurate and early diagnosis of monkeypox virus (MPXV) is crucial for controlling epidemics and treating affected individuals promptly. This study aimed to assess the analytical and clinical performance of the MolecisionTM Monkeypox Virus qPCR Assay ...
Jing Qu, Xiaomin Zhang, Kun Liu, You Li, Ting Wang, Zhonggang Fang, Cheng Chen, Xiao Tan, Ying Lin, Qing Xu, Yan Yang, Wanqing Wang, Manyu Huang, Shiliang Guo, Ziqiu Chen, Wei Rao, Xiaolu Shi, Bo Peng   +17 more
doaj   +1 more source

Evaluation of Monkeypox- and Vaccinia virus-neutralizing antibodies in human serum samples after vaccination and natural infection

Frontiers in Public Health, 2023
IntroductionIn early to mid-2022, an unexpected outbreak of Monkeypox virus infections occurred outside the African endemic regions. Vaccines originally developed in the past to protect against smallpox are one of the available countermeasures to prevent
Alessandro Manenti, Niccolò Solfanelli, Paolo Cantaloni, Livia Mazzini, Margherita Leonardi, Margherita Leonardi, Linda Benincasa, Giulia Piccini, Serena Marchi, Martina Boncioli, Chiara Spertilli Raffaelli, Danilo Tacconi, Giada Mattiuzzo, Otfried Kistner, Emanuele Montomoli, Emanuele Montomoli, Emanuele Montomoli, Claudia Maria Trombetta, Claudia Maria Trombetta   +18 more
doaj   +1 more source