Results 91 to 100 of about 35,566 (181)

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Chalcones: A Valid Scaffold for Monoamine Oxidases Inhibitors

, 2016
A large series of substituted chalcones have been synthesized and tested in vitro for their ability to inhibit human monoamine oxidases A and B (hMAO-A and hMAO-B).
Franco Chimenti (2268034), Francesca Rossi (119260), Francesco Ortuso (480669), Paola Chimenti (805165), Daniela Secci (1456555), Rossella Fioravanti (2100034), Matilde Yáñez (1597858), Stefano Alcaro (152511), Adriana Bolasco (2100031), Francisco Orallo (2209456)   +9 more
core   +1 more source

6‐Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human

Andrology, EarlyView.
ABSTRACT Background Epithelium‐derived catecholamines contribute to local regulation of genitourinary smooth muscle function, but the role of the endogenous 6‐nitrodopamine (6‐ND) in the prostate remains unknown. Objectives To determine whether 6‐ND is produced by mouse and human prostate and its role in smooth muscle regulation.
Alline Araujo Curiel, Fabio Henrique da Silva, Jéssica Mariana Dias, Luise Gabriela Santos Pereira, Douglas Rafael Martins Dias, Amanda Bueno Olivotti, André Almeida Schenka, Valéria Barbosa de Souza, Masato Tsutsui, Fabiola Zakia Monica, Edson Antunes, Gilberto De Nucci, Mariana G. de Oliveira   +12 more
wiley   +1 more source

Menopausal status at the age of 46: Its association with depressive and anxiety symptoms and morbidity in women—A northern Finland birth cohort 1966 study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Women who are perimenopausal or menopausal at age 46 have a higher risk of anxiety and depressive symptoms than premenopausal women. Early‐onset menopause highlights the need for mental health support during and after the menopausal transition. Abstract Introduction The incidence of several morbidities increases during the menopausal transition ...
Tiia Saarinen, Susanna M. Savukoski, Paula Pesonen, Jouko Miettunen, Maarit Niinimäki   +4 more
wiley   +1 more source

Chalcones: A Valid Scaffold for Monoamine Oxidases Inhibitors

, 2009
A large series of substituted chalcones have been synthesized and tested in vitro for their ability to inhibit human monoamine oxidases A and B (hMAO-A and hMAO-B).
CHIMENTI, Paola, Franco Chimenti, Paola, FIORAVANTI, Rossella, Adriana, SECCI, DANIELA, ROSSI, FRANCESCA, Rossella, BOLASCO, Adriana, Daniela   +9 more
core   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Monoamine oxidases : activities, genotypes and the shaping of behaviour

, 2007
The importance of an interaction between environment and biological factors for the expression for a particular behaviour is illustrated by results from a series of adolescents in which effects of platelet MAO activity and psychosocial environment on ...
Nilsson, Kent,, Oreland, Lars,, Damberg, Mattias,, Hallman, Jarmila,, Damberg, M.,, Hallman, J.,, Oreland, L.,, Nilsson, Kent W.,   +7 more
core   +1 more source

Flavonoids from Sideritis Species: Human Monoamine Oxidase (hMAO) Inhibitory Activities, Molecular Docking Studies and Crystal Structure of Xanthomicrol

Molecules, 2015
The inhibitory effects of flavonoids on monoamine oxidases (MAOs) have attracted great interest since alterations in monoaminergic transmission are reported to be related to neurodegenerative diseases such as Parkinson’s and Alzheimer’s diseases and ...
Fatma Pinar Turkmenoglu, İpek Baysal, Samiye Ciftci-Yabanoglu, Kemal Yelekci, Hamdi Temel, Salih Paşa, Nurten Ezer, İhsan Çalış, Gulberk Ucar   +8 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Recent development of monoamine oxidase inhibitors

, 2005
The monoamine oxidases (MAO-A and MAO-B) are flavoenzymes located in the outer mitochondrial membrane responsible for the oxidative deamination of many endogenous and exogenous monoamines.
Fioravanti, R., Simone Carradori, CARRADORI, Simone, Bolasco, A., FIORAVANTI, Rossella, Adriana Bolasco, BOLASCO, Adriana, Rossella Fioravanti   +7 more
core   +1 more source