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Monoclonal Antibodies

New England Journal of Medicine, 1981
Serologic reagents have played an important role in the diagnosis, treatment, and epidemiology of infectious diseases. A new technology has been developed for generating homogeneous antibodies that can be produced in large amounts and are available indefinitely. This technique promises to increase the reliability and sensitivity of immunoassays and may
M D, Scharff, S, Roberts, P, Thammana
openaire   +4 more sources

Monoclonal Antibodies

2008
Monoclonal antibodies (mabs) are powerful tools for the quantification, detection, and targeting of specific molecules. Allergen-specific mabs are important for the quantification of major allergens in allergen preparations used for allergen-specific immunotherapy and allergy diagnosis.
Helga, Kahlert, Oliver, Cromwell
openaire   +2 more sources

Monoclonal Rh antibodies

Revue Francaise de Transfusion et Immuno-hématologie, 1988
The Rh antibodies were studied by manual serological techniques (see Daniels' report on Kell related antigens), using human red cells of common and rare Rh phenotypes in an attempt to identify their specificity and/or usefulness as reagents. The report is divided into 3 sections : section I anti-D antibodies, section II other Rh specifities, section ...
P, Tippett, C, Lomas
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Generating Monoclonal Antibodies

Cold Spring Harbor Protocols, 2022
Antibodies that are produced by hybridomas are known as monoclonal antibodies. Here we introduce methods for generating and screening monoclonal antibodies, including developing the screening procedure and producing hybridomas.
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Monoclonal antibody therapy

Frontiers in Bioscience, 2006
The concept of targeted therapy was conceived through increased understanding of the biological pathways involved in the pathogenesis of cancer and subsequently identification of the most appropriate antigens to target. Monoclonal antibody therapy harnesses host defense mechanisms through activation of the antibody dependent cytotoxic pathway and ...
Deirdre, O'Mahony, Michael R, Bishop
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Monoclonal cryo‐antifibrinogenemia

Arthritis & Rheumatism, 1996
AbstractWe report on a 54‐year‐old female patient with arthritis and a severe cold‐induced leukocytoclastic vasculitis of the skin caused by a rare form of cryofibrinogenemia (“type II” cryofibrinogen). Affinity chromatography of cryoprecipitates from the patient's plasma revealed reversible cryoprecipitability of complexes composed of fibrinogen and a
H H, Euler   +5 more
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New monoclonal antibodies

Current Opinion in Cardiology, 1996
Monoclonal antibody technology has become an important diagnostic and therapeutic tool in many areas of medicine, including the prevention and treatment of organ transplant rejection. The monoclonal antibody that has been most widely used clinically is OKT3, a murine monoclonal antibody directed against the CD3 receptor on the surface of human T cells.
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