Results 141 to 150 of about 138,183 (374)

Relationship between monocyte-to-lymphocyte ratio and anemia: a NHANES analysis

Hematology
Growing evidence supports the significant role of inflammatory factors in anemia. This paper intends to ascertain the potential link between MLR and anemia and explore potential mediators. Our analysis employed comprehensive data recourse from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018 utilizing weighted logistic ...
Yongjin Zhi, Shuojing Bao, Jingcheng Mao, Hui Zhu, Jianfeng Zhu   +4 more
openaire   +2 more sources

DNA hydroxymethylation levels are altered in blood cells from Down syndrome persons enrolled in the MARK-AGE project [PDF]

, 2017
Down syndrome (DS) is caused by the presence of part or an entire extra copy of chromosome 21, a phenomenon that can cause a wide spectrum of clinically defined phenotypes of the disease. Most of the clinical signs of DS are typical of the ageing process
BACALINI, MARIA GIULIA, Breusing, Nicolle, Bürkle, Alexander, CAIAFA, Paola, CALABRESE, ROBERTA, Capri, Miriam, CICCARONE, FABIO, Franceschi, Claudio, Grune, Tilman, GUASTAFIERRO, Tiziana, Malavolta, Marco, Moreno villanueva, María, REALE, Anna, VALENTINI, ELISABETTA, ZAMPIERI, Michele   +14 more
core   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Platelet‑to‑lymphocyte ratio, neutrophil‑to‑lymphocyte ratio and monocyte‑to‑HDL cholesterol ratio as markers of peripheral artery disease in elderly patients.

International Journal of Molecular Medicine, 2020
Solid evidence underlines the pivotal role played by inflammation regarding atherosclerosis. Peripheral artery disease (PAD) is one of atherosclerotic cardiovascular diseases (CVDs), it is highly frequently diagnosed in older individuals.
Stefano Selvaggio, A. Abate, Giuseppe Brugaletta, C. Musso, Mario Di Guardo, Caterina Di Guardo, E. Vicari, M. Romano, S. Luca, S. Signorelli   +9 more
semanticscholar   +1 more source

Effect of synthetic and bovine milk conjugated linoleic acid (CLA) on immune function : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition Science at Massey University [PDF]

, 1999
CLA is a collective name for a mixture of positional and geometrical isomers of linoleic acid (c-9, c-12-octadecadioenic acid) which possess conjugated double bonds.
Zhao, Hui
core  

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

A high monocyte-to-lymphocyte ratio predicts poor prognosis in patients with radical cystectomy for bladder cancer [PDF]

, 2020
Heng Shi, Keyi Wang, Jing Yuan, Weipu Mao, Zonglin Wu, Qunlong Liu, Jinbo Xie, Bo Peng   +7 more
openalex   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio, Lymphocyte-to-Monocyte Ratio and Platelet-to-Lymphocyte Ratio as Predictors of Short- and Long-Term Outcomes in Ischemic Stroke Patients with Atrial Fibrillation

Journal of Inflammation Research
Jiahuan Guo,1 Dandan Wang,1 Jiaokun Jia,1 Jia Zhang,1 Yanfang Liu,1 Jingjing Lu,1,2 Xingquan Zhao,1– 4,* Jing Yan1,* 1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2China ...
Guo J, Wang D, Jia J, Zhang J, Liu Y, Lu J, Zhao X, Yan J   +7 more
doaj  

The prognostic value of preoperative peripheral blood inflammatory biomarkers in extrahepatic cholangiocarcinoma: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundRecent evidence indicates that inflammation plays a major role in the pathogenesis and progression of CCA. This meta-analysis seeks to evaluate the prognostic implications of preoperative inflammatory markers, specifically NLR, PLR, and LMR, in
Di Zeng, Di Zeng, Yaoqun Wang, Yaoqun Wang, Ningyuan Wen, Ningyuan Wen, Jiong Lu, Jiong Lu, Bei Li, Bei Li, Nansheng Cheng, Nansheng Cheng   +11 more
doaj   +1 more source