Results 181 to 190 of about 92,607 (288)

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source

Prognostic Study of Inflammatory Markers in Nasopharyngeal Carcinoma Patients Receiving Intensity-Modulated Radiotherapy

Cancer Management and Research
Linbo Tang,1 Xinjing Li,2 Yongbin Wang,1 Yuanhe Tong1 1Department of Radiation Oncology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, Fujian, 364000, People’s Republic of China; 2Department of Pathology, Longyan First ...
Tang L, Li X, Wang Y, Tong Y
doaj  

Monocyte-to-lymphocyte ratio as an inflammatory biomarker for predicting diabetic peripheral neuropathy in type 2 diabetes mellitus patients. [PDF]

BMC Endocr Disord
Li J, Hu F, Lu X, Shen Y, Chen J, Zhang H.   +5 more
europepmc   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

MONOCYTE TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO AS A PREDICTOR OF DISEASE ACTIVITY IN TAKAYASU’S ARTERITIS [PDF]

Blucher Medical Proceedings, 2019
RENAN RODRIGUES NEVES RIBEIRO DO NASCIMENTO, DANIEL VIANA SILVA E SILVA, RAQUEL MITIE KANNO, LUIZA SÁ E RÊGO TUPINAMBÁ, MARIANA DAVIM FERREIRA GOMES, IGOR BELTRÃO DUARTE FERNANDES, GERMANA RIBEIRO ARAÚJO CARNEIRO DE LUCENA, BRUNA SAVIOLI LOPEZ FERNANDEZ, BRUNA SAVIOLI LOPEZ FERNANDEZ, ALEXANDRE WAGNER SILVA DE SOUZA   +9 more
openaire   +1 more source

Association between the monocyte-to-lymphocyte ratio and 28-day all-cause mortality in sepsis-associated delirium patients: a retrospective study and machine learning. [PDF]

BMC Infect Dis
Zhao Y, Jiang J, Pu J, Yang J, Na A, Ding J, Lu Q, Yang K, Zhu H.   +8 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Euthyroid Sick Syndrome (ESS) and Monocyte-to-Lymphocyte Ratio (MLR) Are Predictors of Complications in Geriatric Hip Fractures: A Single-Center Retrospective Analysis. [PDF]

J Clin Med
Capece G, Di Costa D, Pesare E, Pomponi M, Maccauro V, Comodo RM, Kaplan R, Capece U, Farsetti P, Covino M, Maccauro G, Vitiello R.   +11 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Pre-RAI Monocyte-to-Lymphocyte Ratio Predicts Early and Higher Recurrence Risk in Intermediate-Risk DTC, While PNI and NRI Show No Prognostic Value. [PDF]

Clin Endocrinol (Oxf)
Piticchio T, Galeano F, Volpe S, Prinzi A, Barca I, Scuto A, Le Moli R, Geraci G, Tumminia A, Wolde Sellasie S, Pallotti F, Frasca F.   +11 more
europepmc   +1 more source