Results 201 to 210 of about 138,183 (374)

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu, Fa‐Peng Zhang, Chao Qin, Zhi‐Xiao Song, Cai‐Ni Yang, Shu‐Sheng Lin, Xian‐Huan Yu, Wen‐Rui Wu, Chao‐Qun Liu, Chao Liu, Lei‐Bo Xu   +10 more
wiley   +1 more source

Absolute Monocyte Count and Lymphocyte-Monocyte Ratio Predict Outcome in Nodular Sclerosis Hodgkin Lymphoma: Evaluation Based on Data From 1450 Patients [PDF]

, 2015
Tamar Tadmor, Alessia Bari, Luigi Marcheselli, Stefano Sacchi, Ariel Aviv, Luca Baldini, Paolo G. Gobbi, Samantha Pozzi, Paola Ferri, Maria Christina Cox, Nicola Cascavilla, Emilio Iannitto, Massimo Federico, Aaron Polliack   +13 more
openalex   +1 more source

Atherogenic Index of Plasma, Triglyceride-Glucose Index and Monocyte-to-Lymphocyte Ratio for Predicting Subclinical Coronary Artery Disease [PDF]

, 2020
Yueqiao Si, Wenjun Fan, Chao Han, Jingyi Liu, Lixian Sun   +4 more
openalex   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Clinical diagnostic value of methylated SEPT9 combined with NLR, PLR and LMR in colorectal cancer

BMC Gastroenterology
Purpose This study aimed to investigate clinical diagnostic values of mSEPT9 combined with NLR, PLR and LMR in CRC. Methods 329 subjects composed of 120 CRC patients, 105 polyps patients and 104 healthy participants were prospectively recruited ...
Meiyuan Huang, Shuang Deng, Ming Li, Zhenyu Yang, Jiaxing Guo, Yi Deng, Dongliang Chen, Bokang Yan   +7 more
doaj   +1 more source

Sequential Evaluation of Hematology Markers as a Prognostic Factor in Glioblastoma Patients

Biomedicines
In our study, we investigated the prognostic significance of hematological markers—NLR (Neutrophil-to-Lymphocyte Ratio), PLR (Platelet-to-Lymphocyte Ratio), and RDW-CV (Red Blood Cell Distribution Width—Coefficient of Variation)—in 117 glioblastoma ...
João Meira Gonçalves, Bruno Carvalho, Rui Tuna, Patricia Polónia, Paulo Linhares   +4 more
doaj   +1 more source

Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]

, 2013
The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M., Hadjati, J., Latifpour, M., Masoud, A., Nicknam, M.H., Nikbin, B., Saeidi, M., Shakiba, Y.   +7 more
core  

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

A novel score using lymphocyte to monocyte ratios for predicting the disease recurrence of ovarian cancer patients with malignant body fluid

, 2023
Min Jin Jeong, Yong Seok Lee, Ji Su Mun
openalex   +1 more source

The role of neutrophil-lymphocyte ratio and lymphocyte–monocyte ratio in the prognosis of type 2 diabetics with COVID-19 [PDF]

, 2020
Gaoli Liu, Shaowen Zhang, Haifeng Hu, Tingting Liu, Jie Huang   +4 more
openalex   +1 more source