Results 241 to 250 of about 90,200,282 (296)

Association of monocyte to lymphocyte ratio with length of stay in intensive care unit in neonatal apnea modified by treatment. [PDF]

Transl Pediatr
Chen J, Han F.
europepmc   +1 more source

Composite Inflammatory Score for Predicting Progression‐Free Survival in Metastatic Clear Cell Renal Cell Carcinoma Treated With First‐Line Toripalimab Plus Axitinib

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Routine inflammatory and nutritional markers may help stratify progression risk in metastatic clear cell renal cell carcinoma during immunotherapy‐based treatment. This single‐center retrospective study included 237 patients who received first‐line toripalimab plus axitinib therapy.
Yun‐Feng Wu, Jing‐Suo Wang, Chuan‐Ao Zhang, Fan Zhang, Zhi‐Yu Zhang   +4 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Association between monocyte-to-lymphocyte ratio and cardiovascular diseases: insights from NHANES data. [PDF]

Diabetol Metab Syndr
Li X, Zhang L, Du Y, Shen Y, Gong Y, Wang J, Zhou J, Wang S.   +7 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Rethinking colitis: MrgprD puts macrophages in the driver's seat†

The Journal of Pathology, EarlyView.
Abstract There is increasing evidence to suggest that dysregulated macrophages play an important role in the promotion and maintenance of inflammatory bowel disease (IBD), yet the underlying mechanisms remain unclear. A recent study published by Lv, Xia, Qiao et al in The Journal of Pathology investigated the role of Mas‐related G protein‐coupled ...
Kolja Pocha, Konstantin Bräutigam
wiley   +1 more source

Structural and functional brain correlates of the neutrophil- and monocyte-to-lymphocyte ratio in neuropsychiatric disorders. [PDF]

Brain Behav Immun Health
McIntosh R.
europepmc   +1 more source

Top‐Down CSF Peptidomics Reveals Disease‐Associated Peptide Signatures and Oxidative Modifications in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

PROTEOMICS, EarlyView.
ABSTRACT Multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory demyelinating diseases of the CNS whose diagnosis is mainly based on clinical evidence, magnetic resonance imaging, and the analysis of cerebrospinal fluid (CSF). Current approaches provide only partial insight into disease‐related biological processes, thus
Cristina Contini, Lorena Lorefice, Greca Lai, Alessandra Schirru, Giorgia Zodio, Tiziana Cabras, Alessandra Olianas, Giacomo Diaz, Eleonora Cocco, Barbara Manconi   +9 more
wiley   +1 more source

Predictive value of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio for three-year survival in patients with early esophageal cancer undergoing endoscopic submucosal dissection. [PDF]

Front Oncol
Zheng Y, Zhang H, Su Y, Zhang J, Xu W, Pan W, Li Z.   +6 more
europepmc   +1 more source

Recompensation of Cirrhosis: A New Treatment‐Related Disease State

Portal Hypertension &Cirrhosis, EarlyView.
This perspective article conceptualizes recompensation of cirrhosis as a distinct treatment‐related disease state rather than mere transient clinical improvement after etiology‐directed therapy, and further proposes a four‐state classification including compensated cirrhosis, stable recompensation, unstable recompensation, and persistent decompensation
Wentao Tan, Zhiying He, Shuai Xia, Luqi Tang, Hong You, Bingqiong Wang   +5 more
wiley   +1 more source