Results 251 to 260 of about 90,200,282 (296)

Association between monocyte-to-lymphocyte ratio and mortality in patients with acute pancreatitis requiring intensive care unit admission: a retrospective cohort study and predictive model establishment based on machine learning. [PDF]

Sci Rep
Yang J, Dong C, Guo M, Chen J, Zou H, Gao H, Xu J, Liu Y, Wu W, Yang S.   +9 more
europepmc   +1 more source

Melittin Reprograms Tumor‐Associated Macrophages Through CD18‐Mediated Immunomodulation

Phytotherapy Research, EarlyView.
Melittin selectively targets CD18 to deplete M2‐TAMs and remodel the TME to suppress tumor growth. ABSTRACT Tumor‐associated macrophages (TAMs), particularly the M2‐like subtype, contribute to an immunosuppressive tumor microenvironment and promote tumor progression.
Ik‐Hwan Han, Hyunju Lee, Eunbin Ko, Ilseob Choi, Soyoung Kim, Deok‐Sang Hwang, Hyunsu Bae   +6 more
wiley   +1 more source

Association of neutrophil-to-lymphocyte ratio (NLR) and neutrophil-to-monocyte-to-lymphocyte ratio (NMLR) with mortality in adults with osteoarthritis: Evidence from NHANES 2001 to 2018. [PDF]

Medicine (Baltimore)
Kang J, Xin S, Zhang H, Wang T, Zhao K, Gao X, Wang Y.   +6 more
europepmc   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

Elevated neutrophil-monocyte-to-lymphocyte ratio increases risk of adverse outcomes in patients with chronic kidney disease and type 2 diabetes. [PDF]

Eur J Med Res
Li HL, Dong LP, Wei HL, Li H, Tian M, Dong JW.   +5 more
europepmc   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

The Associations of Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Systemic Immune-Inflammatory Index with the Severity and Prognosis of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy. [PDF]

J Inflamm Res
Han A, Xie Y, Sun W, Zhou X, Zhang S, Xie Y, Yang N, Xie N.   +7 more
europepmc   +1 more source

Preoperative monocyte-to-lymphocyte ratio as a prognosis predictor after curative hepatectomy for intrahepatic cholangiocarcinoma. [PDF]

BMC Cancer
Tao BF, Zhu HQ, Qi LN, Zhong JH, Mai RY, Ma L.   +5 more
europepmc   +1 more source

Corrigendum to "Monocyte-to-lymphocyte ratio affects prognosis in LAA-type stroke patients" [Heliyon Volume 8, Issue 10, October 2022, Article e10948]. [PDF]

Heliyon
Wang CJ, Pang CY, Huan-Yu, Cheng YF, Wang H, Deng BB, Huang HJ.   +6 more
europepmc   +1 more source