Results 91 to 100 of about 90,200,325 (293)

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

The preoperative neutrophil-to-lymphocyte ratio predictive value for survival in patients with brain metastasis

, 2022
Background The neutrophil-to-lymphocyte (NLR), monocyte-to-lymphocyte (MLR), platelet-to-lymphocyte ratio (PLR), and red blood cell distribution width (RDW) have been previously studied as predictors of survival in different ...
Davi Jorge Fontoura Solla, Bruno Spindola Amaral Garcia de Freitas, Manoel Jacobsen Teixeira, Vitor Nagai Yamaki, Helder Picarelli, Iuri Santana Neville, Alexandra Gomes dos Santos, Wellingson Silva Paiva, Calvin Diep, Eberval Gadelha Figueiredo   +9 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Are the Neutrophil-to-lymphocyte Ratio and Lymphocyte-to-monocyte Ratio Prognostic Markers in Elderly Patients with Diffuse Large B-cell Lymphoma?

Acta Haematologica Oncologica Turcica
Aim: Neutrophil-to-lymphocyte ratio (NLR) and lymphocyte-to-monocyte ratio (LMR) are inflammatory markers that have been studied as prognostic factors in diffuse large B-cell lymphoma (DLBCL).
Büşra Tuğçe Tonyalı, Deniz Arıca, Ebru Koca, Sema Karakuş, Şahika Zeynep Akı   +4 more
doaj   +1 more source

DataSheet_1_Prognostic Significance of Pretreatment Neutrophil-to-Lymphocyte Ratio, Platelet−to−Lymphocyte Ratio, or Monocyte-to-Lymphocyte Ratio in Endometrial Neoplasms: A Systematic Review and Meta−analysis.zip

, 2022
AimNeutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), or monocyte–lymphocyte ratio (MLR) has been shown to be related to the poor prognosis of cervical cancer, ovarian cancer, breast cancer, and other malignant tumors, but their role in ...
Lihui Zhang (482145), Fei Wu (117860), Jiali Leng (10707984)   +2 more
core   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

The “Goldilocks Zone” of immune balance: association of neutrophil-to-lymphocyte and lymphocyte-to-monocyte ratios with miscarriage

Frontiers in Global Women's Health
BackgroundMiscarriage affects 15%–20% of clinically recognized pregnancies, yet reliable biomarkers for risk stratification remain elusive. While systemic inflammatory markers derived from routine complete blood count have shown promise in identifying ...
Zhou Fang, Nan Ding, Fang Wang
doaj   +1 more source

Correlation between plasma fibrinogen level and inflammatory parameters (i.e., leukocyte, neutrophil and platelet counts, neutrophil-lymphocyte ratio, and lymphocyte-monocyte ratio).

, 2016
Correlation between plasma fibrinogen level and inflammatory parameters (i.e., leukocyte, neutrophil and platelet counts, neutrophil-lymphocyte ratio, and lymphocyte-monocyte ratio).
Shuai Hu (838232), Cheng Shen (838231), Yi Song (105202), Jun Li (6494), Lei Zhang (38117), Wen-Ke Han (838233), Li-Qun Zhou (838229), Bo Zhang (6559), Yu Fan (111503), Cong Wang (107450), Xiao-Yu Chen (342645), Wei Yu (43094), Zhi-Song He (838230), Li-Bo Liu (2547382), Jie Jin (52722), Qun He (166307)   +15 more
core   +1 more source

Data Excel sheet for Study of differential neutrophil to lymphocyte ratio and differential monocyte to lymphocyte ratio in patients with Tuberculosis in a coastal city of India.

, 2023
This is the data collection sheet for the study  Study of differential neutrophil to lymphocyte ratio and differential monocyte to lymphocyte ratio in patients with Tuberculosis in a coastal city of India. 
Sharada Rai (14800669), Rakshatha Nayak (14677751)   +1 more
core   +1 more source