Results 241 to 250 of about 90,200,325 (293)

Structural and functional brain correlates of the neutrophil- and monocyte-to-lymphocyte ratio in neuropsychiatric disorders. [PDF]

Brain Behav Immun Health
McIntosh R.
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Predictive value of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio for three-year survival in patients with early esophageal cancer undergoing endoscopic submucosal dissection. [PDF]

Front Oncol
Zheng Y, Zhang H, Su Y, Zhang J, Xu W, Pan W, Li Z.   +6 more
europepmc   +1 more source

Rethinking colitis: MrgprD puts macrophages in the driver's seat†

The Journal of Pathology, EarlyView.
Abstract There is increasing evidence to suggest that dysregulated macrophages play an important role in the promotion and maintenance of inflammatory bowel disease (IBD), yet the underlying mechanisms remain unclear. A recent study published by Lv, Xia, Qiao et al in The Journal of Pathology investigated the role of Mas‐related G protein‐coupled ...
Kolja Pocha, Konstantin Bräutigam
wiley   +1 more source

Association between monocyte-to-lymphocyte ratio and mortality in patients with acute pancreatitis requiring intensive care unit admission: a retrospective cohort study and predictive model establishment based on machine learning. [PDF]

Sci Rep
Yang J, Dong C, Guo M, Chen J, Zou H, Gao H, Xu J, Liu Y, Wu W, Yang S.   +9 more
europepmc   +1 more source

Top‐Down CSF Peptidomics Reveals Disease‐Associated Peptide Signatures and Oxidative Modifications in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

PROTEOMICS, EarlyView.
ABSTRACT Multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory demyelinating diseases of the CNS whose diagnosis is mainly based on clinical evidence, magnetic resonance imaging, and the analysis of cerebrospinal fluid (CSF). Current approaches provide only partial insight into disease‐related biological processes, thus
Cristina Contini, Lorena Lorefice, Greca Lai, Alessandra Schirru, Giorgia Zodio, Tiziana Cabras, Alessandra Olianas, Giacomo Diaz, Eleonora Cocco, Barbara Manconi   +9 more
wiley   +1 more source

Association of neutrophil-to-lymphocyte ratio (NLR) and neutrophil-to-monocyte-to-lymphocyte ratio (NMLR) with mortality in adults with osteoarthritis: Evidence from NHANES 2001 to 2018. [PDF]

Medicine (Baltimore)
Kang J, Xin S, Zhang H, Wang T, Zhao K, Gao X, Wang Y.   +6 more
europepmc   +1 more source

Recompensation of Cirrhosis: A New Treatment‐Related Disease State

Portal Hypertension &Cirrhosis, EarlyView.
This perspective article conceptualizes recompensation of cirrhosis as a distinct treatment‐related disease state rather than mere transient clinical improvement after etiology‐directed therapy, and further proposes a four‐state classification including compensated cirrhosis, stable recompensation, unstable recompensation, and persistent decompensation
Wentao Tan, Zhiying He, Shuai Xia, Luqi Tang, Hong You, Bingqiong Wang   +5 more
wiley   +1 more source

Elevated neutrophil-monocyte-to-lymphocyte ratio increases risk of adverse outcomes in patients with chronic kidney disease and type 2 diabetes. [PDF]

Eur J Med Res
Li HL, Dong LP, Wei HL, Li H, Tian M, Dong JW.   +5 more
europepmc   +1 more source

Melittin Reprograms Tumor‐Associated Macrophages Through CD18‐Mediated Immunomodulation

Phytotherapy Research, EarlyView.
Melittin selectively targets CD18 to deplete M2‐TAMs and remodel the TME to suppress tumor growth. ABSTRACT Tumor‐associated macrophages (TAMs), particularly the M2‐like subtype, contribute to an immunosuppressive tumor microenvironment and promote tumor progression.
Ik‐Hwan Han, Hyunju Lee, Eunbin Ko, Ilseob Choi, Soyoung Kim, Deok‐Sang Hwang, Hyunsu Bae   +6 more
wiley   +1 more source