Results 61 to 70 of about 264,703 (294)
Guardians of the actin monomer
European Journal of Cell Biology, 2013 Actin is a universal force provider in eukaryotic cells. Biological processes harness the pressure generated from actin polymerization through dictating the time, place and direction of filament growth. As such, polymerization is initiated and maintained via tightly controlled filament nucleation and elongation machineries. Biological systems integrate
Bo Xue, Robert Robinson, Robert Robinson
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FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada +3 more
wiley +1 more source
Theory of monomer-dimer systems [PDF]
Communications in Mathematical Physics, 1972 We investigate the general monomer-dimer partition function, P(x), which is a polynomial in the monomer activity, x, with coefficients depending on the dimer activities. Our main result is that P(x) has its zeros on the imaginary axis when the dimer activities are nonnegative. Therefore, no monomer-dimer system can have a phase transition as a function
Heilmann, Ole J., Lieb, Elliott H.
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Central Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
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Chaperonin of Group I: Oligomeric Spectrum and Biochemical and Biological Implications
Frontiers in Molecular Biosciences, 2018 Chaperonins play various physiological roles and can also be pathogenic. Elucidation of their structure, e.g., oligomeric status and post-translational modifications (PTM), is necessary to understand their functions and mechanisms of action in health and
Silvia Vilasi +13 more
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Arthritis Care &Research, EarlyView.Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp +8 more
wiley +1 more source
Studies on Monomer Sequences in Polyesters Having Asymmetric Monomers [PDF]
Polymer Journal, 1972 NMR spectra of homopolyesters containing asymmetric monomers, which were obtained by ordinary molten-state polycondensation under reduced pressure, are studied.Poly(propylene terephthalate), poly(propylene malonate), poly(propylene succinate), poly(ethylene itaconate), and poly(ethylene methylsuccinate), which have asymmetric glycols or acids, show ...
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